ArticlePlant cell reports2012
Changes in micro RNA expression in a wild tuber-bearing Solanum species induced by 5-Azacytidine treatment.
Article in Plant cell reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Demethylating drugs alter protoplast development, regeneration, and the genome stability of protoplast-derived regenerants of cabbage.BMC plant biology · 2025Article
- The Good, the Bad, and the Epigenetic: Stress-Induced Metabolite Regulation and Transgenerational Effects.Epigenomes · 2025Review
- Assessing small RNA profiles in potato diploid hybrid and its resynthesized allopolyploid reveals conserved abundance with distinct genomic distribution.Plant cell reports · 2024Article
- Genome-wide association study of 23 flowering phenology traits and 4 floral agronomic traits in tree peony (Horticulture research · 2023Article
- Stochastic Variation in DNA Methylation Modulates Nucleosome Occupancy and Alternative Splicing inPlants (Basel, Switzerland) · 2022Article
- Feasible strategies for studying the involvement of DNA methylation and histone acetylation in the stress-induced formation of quality-related metabolites in tea (Camellia sinensis).Horticulture research · 2021Review
- Article
- Target of Rapamycin Regulates Genome Methylation Reprogramming to Control Plant Growth inFrontiers in genetics · 2020Article
- Evidence for novel epigenetic marks within plants.AIMS genetics · 2019Article
- Transcriptome Profiling Reveals Transcriptional Regulation by DNA Methyltransferase Inhibitor 5-Aza-2'-Deoxycytidine Enhancing Red Pigmentation in Bagged "Granny Smith" Apples (International journal of molecular sciences · 2018Article
- 5-Azacytidine mediated reactivation of silenced transgenes in potato (Solanum tuberosum) at the whole plant level.Plant cell reports · 2017Article
- Quantitative trait variation is revealed in a novel hypomethylated population of woodland strawberry (Fragaria vesca).BMC plant biology · 2016Article
- Stable Epigenetic Variants Selected from an Induced HypomethylatedFrontiers in plant science · 2016Article
- Genome-wide mapping of 5-hydroxymethylcytosine in three rice cultivars reveals its preferential localization in transcriptionally silent transposable element genes.Journal of experimental botany · 2015Article
- DNA methylation and transcriptomic changes in response to different lights and stresses in 7B-1 male-sterile tomato.PloS one · 2015Article
- Sustainable harvest: managing plasticity for resilient crops.Plant biotechnology journal · 2014Review
- Article
- Epigenetic patterns newly established after interspecific hybridization in natural populations of Solanum.Ecology and evolution · 2013Article
- Chemical probes in plant epigenetics studies.Plant signaling & behavior · 2013Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phenotypic plasticity is often postulated as a principal characteristic of tuber-bearing wild Solanum species. The hypotheses to explore this observation have been developed based on the presence of genetic variation. In this context, evolutionary changes and adaptation are impossible without genetic variation. However, epigenetic effects, which include DNA methylation and microRNAs expression control, could be another source of phenotypic variation in ecologically relevant traits. To achieve a detailed mechanistic understanding of these processes, it is necessary to separate epigenetic from DNA sequence-based effects and to evaluate their relative importance on phenotypic variability. We explored the potential relevance of epigenetic effects in individuals with the same genotype. For this purpose, a clone of the wild potato Solanum ruiz-lealii, a non-model species in which natural methylation variability has been demonstrated, was selected and its DNA methylation was manipulated applying 5-Azacytidine (AzaC), a demethylating agent. The AzaC treatment induced early flowering and changes in leaf morphology. Using quantitative real-time PCR, we identified four miRNAs up-regulated in the AzaC-treated plants. One of them, miRNA172, could play a role on the early flowering phenotype. In this work, we showed that the treatment with AzaC could provide meaningful results allowing to study both the phenotypic plasticity in tuber-bearing Solanum species and the inter-relation between DNA methylation and miRNA accumulations in a wide range of species.
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