ArticleBreast cancer research and treatment2012
Quality of life over time in women diagnosed with ductal carcinoma in situ, early-stage invasive breast cancer, and age-matched controls.
Article in Breast cancer research and treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quality of life issues in patients with ductal carcinoma in situ: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Factors associated with initiation and continuation of endocrine therapy in women with hormone receptor-positive breast cancer.BMC cancer · 2022Trial
- Randomized controlled trial of a breast cancer Survivor Stories intervention for African American women.Social science & medicine (1982) · 2021Trial
- Influence of built environment on quality of life changes in African-American patients with non-metastatic breast cancer.Health & place · 2020Trial
- Perceived social support in African American breast cancer patients: Predictors and effects.Social science & medicine (1982) · 2017Trial
- Higher-intensity exercise helps cancer survivors remain motivated.Journal of cancer survivorship : research and practice · 2016Trial
- Health-related Quality of Life of Breast Cancer Survivors Attending an Exercise Intervention Study: A Five-year Follow-up.In vivo (Athens, Greece)Trial
- Health-related quality of life among women diagnosed with in situ or invasive breast cancer and age-matched controls: a population-based study.Journal of patient-reported outcomes · 2024Article
- Article
- Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up Study.Cancers · 2023Article
- Quality of life among women with symptomatic, screen-detected, and interval breast cancer, and for women without breast cancer: a retrospective cross-sectional study from Norway.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Are there sustained psychological impacts in women diagnosed with in-situ or early invasive breast cancers?Frontiers in global women's health · 2022Article
- Evaluation of Long-Term Satisfaction with Breast Surgery in Patients Treated for Ductal Carcinoma In Situ: A Population-Based Longitudinal Cohort Study.Annals of surgical oncology · 2020Article
- Ductal carcinoma in situ (DCIS): The importance of patient-reported outcomes (PRO).Current breast cancer reports · 2020Article
- Primary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case-control study.Scientific reports · 2020Article
- Psychological morbidity in women diagnosed with ductal carcinoma in situ compared with women with early breast cancer receiving radiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- A Prospective Study of Weight Gain in Women Diagnosed with Early-Stage Invasive Breast Cancer, Ductal CarcinomaJournal of women's health (2002) · 2020Article
- Article
- Interventions are needed to support patient-provider decision-making for DCIS: a scoping review.Breast cancer research and treatment · 2018Article
- Accelerated partial breast irradiation compared with whole breast radiation therapy: a breast cancer cohort study measuring change in radiation side-effects severity and quality of life.Breast cancer research and treatment · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Little is known about quality-of-life (QOL) differences over time between incident ductal carcinoma in situ (DCIS) and early-stage invasive breast cancer (EIBC) cases as compared with same-aged women without breast cancer (controls). We prospectively recruited and interviewed 1,096 women [16.8% DCIS, 33.3% EIBC (25.7% Stage I; and 7.6% Stage IIA), 49.9% controls; mean age 58; 23.7% non-white] at mean 6.7 weeks (T1), and 6.2 (T2), 12.3 (T3), and 24.4 months (T4) after surgery (patients) or screening mammogram (controls). We tested two hypotheses: (1) DCIS patients would report lower levels of QOL compared with controls but would report similar QOL compared with EIBC patients at baseline; and (2) DCIS patients' QOL would improve during 2-year follow-up and approach levels similar to that of controls faster than EIBC patients. We tested hypothesis 1 using separate general linear regression models for each of the eight subscales on the RAND 36-item Health Survey, controlling for variables associated with at least one subscale at T1. Both DCIS and EIBC patients reported lower QOL at T1 than controls on all subscales (each P<0.05). We tested hypothesis 2 using generalized estimating equations to examine change in each QOL subscale over time across the three diagnostic groups adjusting for covariates. By T3, physical functioning, role limitations due to physical problems, energy/fatigue, and general health each differed significantly by diagnostic group at P<0.05, because of larger differences between EIBC patients and controls; but DCIS patients no longer differed significantly from controls on any of the QOL subscales. At T4, EIBC patients still reported worse physical functioning (P=0.0001) and general health (P=0.0017) than controls, possibly because of lingering treatment effects. DCIS patients' QOL was similar to that of controls two years after diagnosis, but some aspects of EIBC patients' QOL remained lower.
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