ArticleClinical research in cardiology : official journal of the German Cardiac Society2012
Impact of chronic obstructive pulmonary disease severity on symptoms and prognosis in patients with systolic heart failure.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Chronic obstructive pulmonary disease and risk of incident cardiovascular disease, chronic kidney disease, and death: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Implications of Managing Chronic Obstructive Pulmonary Disease in Cardiovascular Diseases.Tuberculosis and respiratory diseases · 2021Article
- Lung function evaluation in heart failure: possible pitfalls.Breathe (Sheffield, England) · 2020Article
- Association of Medication Intensity and Stages of Airflow Limitation With the Risk of Hospitalization or Death in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease.JAMA network open · 2018Article
- The prognostic significance of lung function in stable heart failure outpatients.Clinical cardiology · 2017Article
- Predictors of Post-discharge Mortality Among Patients Hospitalized for Acute Heart Failure.Cardiac failure review · 2017Article
- Korean Guidelines for Diagnosis and Management of Chronic Heart Failure.Korean circulation journal · 2017Review
- Identifying the heterogeneity of COPD by V/P SPECT: a new tool for improving the diagnosis of parenchymal defects and grading the severity of small airways disease.International journal of chronic obstructive pulmonary disease · 2017Article
- Modified Medical Research Council scale vs Baseline Dyspnea Index to evaluate dyspnea in chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2015Article
- The future of chronic disease management: melting pot or mosaic?Physiotherapy Canada. Physiotherapie Canada · 2015Article
- Serial pulmonary function tests to diagnose COPD in chronic heart failure.Translational respiratory medicine · 2014Article
- Differences in clinical characteristics, management and short-term outcome between acute heart failure patients chronic obstructive pulmonary disease and those without this co-morbidity.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Observational
- Risk of atrial fibrillation, stroke, and death after radiofrequency catheter ablation of typical atrial flutter.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Observational
- Comparison of modification of diet in renal disease and chronic kidney disease epidemiology collaboration formulas in predicting long-term outcomes in patients undergoing stent implantation due to stable coronary artery disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Article
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13 authors.
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Abstract
backgroundSystolic heart failure (SHF) and chronic obstructive pulmonary disease (COPD) are frequently associated. The purpose of our study was to explore the impact of COPD severity on symptoms and prognosis in patients with SHF. METHODS AND
resultsChronic obstructive pulmonary disease was systematically screened by spirometry in 348 patients admitted for SHF from April 2002 to December 2006. Severity of COPD was defined according to the GOLD classification. Prevalence of COPD was 37.9 %. Patients' distribution according to GOLD stages I, II, II and IV were, respectively, 51.5, 37.9, 7.6 and 3.0 %. Severity of dyspnoea increases with GOLD stage. There was a significant correlation between NYHA stage and left ventricular ejection fraction in patients without COPD (R (2) = 0.03; P = 0.01) but not in patients with COPD. Mean follow-up was of 54.9 ± 27.4 months. Mortality was 46.6 % and was highest in the COPD group (53.8 vs. 42.3 %; P = 0.049). Kaplan-Meier survival curves showed that patients with GOLD stage I had the same prognosis than patients without COPD and mortality increased from GOLD stage II to stage IV. After multivariate analysis, GOLD stage and diuretics' dose were independently associated with mortality.
conclusionsChronic obstructive pulmonary disease is frequent in patients with SHF and increases mortality. Since dyspnoea is poorly specific of COPD in chronic heart failure patients, COPD remains underdiagnosed thus leading to inappropriate increase of diuretics' dose. COPD should be systematically screened in patients with SHF to adapt prescription of selective β1-blockers, and diuretics' dose and reduce the exposition to risk factors.
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