ArticleContemporary clinical trials2012
Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: the TEDDY Study.
Article in Contemporary clinical trials, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Strategies to increase participant diversity in pediatric research: a systematic review.Pediatric research · 2026Pooled it
- Psychosocial implications, acceptability and ethics of screening for paediatric type 1 diabetes: a systematic review and mixed methods evidence synthesis.Diabetologia · 2026Pooled it
- Parental Views of Facilitators and Barriers to Research Participation: Systematic Review.Pediatrics · 2023Pooled it
- Research Burden in Pediatric Cancer: A Mixed Methods Study From the PediQUEST Response Trial.Journal of pain and symptom management · 2025Trial
- Sugarsquare, a Web-Based Patient Portal for Parents of a Child With Type 1 Diabetes: Multicenter Randomized Controlled Feasibility Trial.Journal of medical Internet research · 2017Trial
- Increasing Trends in Hospitalisation With Diabetic Ketoacidosis at Type 1 Diabetes Diagnosis Among Children and Youth in the United States and England, 2002-2020.Diabetes, obesity & metabolism · 2026Article
- Clasen et al. respond to "Thyroid autoimmunity in the TEDDY cohort: is HLA 8.1 haplotype the hidden driver?"American journal of epidemiology · 2026Article
- Child and mother study satisfaction in a longitudinal study of children at-risk for type 1 diabetes.BMC pediatrics · 2026Observational
- Experiences of families using an early example of a neighbourhood multidisciplinary care team for children and young people in Birmingham, UK: a qualitative exploration of acceptability.Frontiers in pediatrics · 2026Article
- Psychological Impact of Screening for Risk of Type 1 Diabetes: an Update.Current diabetes reports · 2025Review
- Unfolding the Mystery of Autoimmunity: The Environmental Determinants of Diabetes in the Young (TEDDY) Study.Diabetes care · 2025Review
- The efficacy of islet autoantibody screening with or without genetic pre-screening strategies for the identification of presymptomatic type 1 diabetes.Diabetologia · 2025Article
- Looking back at the TEDDY study: lessons and future directions.Nature reviews. Endocrinology · 2025Review
- Factors assessed in the first year of a longitudinal study predict subsequent study visit compliance: the TEDDY study.European journal of medical research · 2023Article
- SAI-CH-6: Development of a Short Form of the State Anxiety Inventory for Children At-Risk for Type 1 Diabetes.Journal of pediatric psychology · 2023Article
- Barriers to and solutions for representative inclusion across the lifespan and in life course research: The need for structural competency highlighted by the COVID-19 pandemic.Journal of clinical and translational science · 2023Review
- Bayesian Joint Modeling of Multivariate Longitudinal and Survival Data With an Application to Diabetes Study.Frontiers in big data · 2022Article
- First-appearing islet autoantibodies for type 1 diabetes in young children: maternal life events during pregnancy and the child's genetic risk.Diabetologia · 2021Article
- Sensing everyday activity: Parent perceptions and feasibility.Infant behavior & development · 2021Article
- Community midwives' and health visitors' experiences of research recruitment: a qualitative exploration using the Theoretical Domains Framework.Primary health care research & development · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 5 countries.
Funding
Abstract
objectiveThe TEDDY Study is an international, multi-center prospective study designed to identify the environmental triggers of type 1 diabetes (T1D) in genetically at-risk children. This report investigates ethnic minority (EM) differences in patterns of enrollment and retention in the US centers.
methodsAs of June 2009, 267,739 newborns had been screened at birth for high risk T1D genotypes. Data collected at the time of screening, enrollment and at the baseline visit were used. Descriptive and multiple-logistic regression analyses assessed differences between EM groups regarding exclusion, enrollment and early withdrawal.
resultsOf the 10,975 eligible subjects, 6,912 (67%) were invited to participate. EM subjects were more likely to be excluded because of an inability to contact. Of those invited 3,265 (47%) enrolled by the age of 4.5 months. Adjusted analyses showed that except for those classified as other EM, the odds of enrolling were similar across groups. EM subjects had elevated early withdrawal rates. Adjusted models demonstrated that this was significantly more likely among Hispanic subjects.
conclusionUnderstanding patterns associated with EM participation in research extends our ability to make more accurate inferences and permits assessment of strategies that promote inclusion of EM to better address health disparities.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.