ReviewBiochimica et biophysica acta2012
Complex dynamics of transcription regulation.
Review in Biochimica et biophysica acta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Structural basis for cell type specific DNA binding of C/EBPβ: The case of cell cycle inhibitor p15INK4b promoter.Journal of structural biology · 2022Article
- Endocrine disruptors of sex hormone activities.Molecular and cellular endocrinology · 2022Review
- A model explaining mRNA level fluctuations based on activity demands and RNA age.PLoS computational biology · 2021Article
- Bayesian modeling of factorial time-course data with applications to a bone aging gene expression study.Journal of applied statistics · 2021Article
- Markovian approaches to modeling intracellular reaction processes with molecular memory.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility.Molecular cell · 2019Article
- CREB-B acts as a key mediator of NPF/NO pathway involved in phase-related locomotor plasticity in locusts.PLoS genetics · 2019Article
- A Model of Glucocorticoid Receptor Interaction With Coregulators Predicts Transcriptional Regulation of Target Genes.Frontiers in pharmacology · 2019Article
- Clustering gene expression time series data using an infinite Gaussian process mixture model.PLoS computational biology · 2018Article
- Pluralistic and stochastic gene regulation: examples, models and consistent theory.Nucleic acids research · 2016Article
- Stress and glucocorticoid receptor transcriptional programming in time and space: Implications for the brain-gut axis.Neurogastroenterology and motility · 2016Review
- Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing.Genome research · 2015Article
- Chromatin structure and gene regulation: a dynamic view of enhancer function.Nucleus (Austin, Tex.) · 2015Article
- DGCR14 induces Il17a gene expression through the RORγ/BAZ1B/RSKS2 complex.Molecular and cellular biology · 2015Article
- Dynamic regulation of transcriptional states by chromatin and transcription factors.Nature reviews. Genetics · 2014Review
- Promoter-mediated transcriptional dynamics.Biophysical journal · 2014Article
- Histone deacetylase 1 and p300 can directly associate with chromatin and compete for binding in a mutually exclusive manner.PloS one · 2014Article
- Steroid receptor-DNA interactions: toward a quantitative connection between energetics and transcriptional regulation.Nucleic acids research · 2014Review
- An evolving understanding of nuclear receptor coregulator proteins.Journal of molecular endocrinology · 2013Review
- C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements.The EMBO journal · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Transcription is a tightly regulated cellular function which can be triggered by endogenous (intrinsic) or exogenous (extrinsic) signals. The development of novel techniques to examine the dynamic behavior of transcription factors and the analysis of transcriptional activity at the single cell level with increased temporal resolution has revealed unexpected elements of stochasticity and dynamics of this process. Emerging research reveals a complex picture, wherein a wide range of time scales and temporal transcription patterns overlap to generate transcriptional programs. The challenge now is to develop a perspective that can guide us to common underlying mechanisms, and consolidate these findings. Here we review the recent literature on temporal dynamics and stochastic gene regulation patterns governed by intrinsic or extrinsic signals, utilizing the glucocorticoid receptor (GR)-mediated transcriptional model to illustrate commonality of these emerging concepts. This article is part of a Special Issue entitled: Chromatin in time and space.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.