ReviewCurrent opinion in biotechnology2012
Cell-free biology: exploiting the interface between synthetic biology and synthetic chemistry.
Review in Current opinion in biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- The Use of Cell-free Protein Synthesis to Push the Boundaries of Synthetic Biology.Biotechnology and bioprocess engineering : BBE · 2023Review
- Advancing synthetic biology through cell-free protein synthesis.Computational and structural biotechnology journal · 2023Review
- Permeability-Engineered Compartmentalization Enables In Vitro Reconstitution of Sustained Synthetic Biology Systems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity.Autophagy · 2022Article
- Enhanced regulation of prokaryotic gene expression by a eukaryotic transcriptional activator.Nature communications · 2021Article
- Microfluidic cap-to-dispense (μCD): a universal microfluidic-robotic interface for automated pipette-free high-precision liquid handling.Lab on a chip · 2019Article
- On a Robust, Sensitive Cell-Free Method forMicromachines · 2019Article
- Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography.Journal of visualized experiments : JoVE · 2018Article
- Cell-free synthesis of stable isotope-labeled internal standards for targeted quantitative proteomics.Synthetic and systems biotechnology · 2018Review
- In vitro transcription-translation using bacterial genome as a template to reconstitute intracellular profile.Nucleic acids research · 2017Article
- Multi-dimensional studies of synthetic genetic promoters enabled by microfluidic impact printing.Lab on a chip · 2017Article
- Cell-free synthetic biology forBiochemical Society transactions · 2017Review
- Sequence homolog-based molecular engineering for shifting the enzymatic pH optimum.Synthetic and systems biotechnology · 2016Article
- High-yield hydrogen production from biomass by in vitro metabolic engineering: Mixed sugars coutilization and kinetic modeling.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Early engineering approaches to improve peptide developability and manufacturability.The AAPS journal · 2015Review
- Synthetic Biology: A Bridge between Artificial and Natural Cells.Life (Basel, Switzerland) · 2014Review
- Cell-free protein synthesis from a release factor 1 deficient Escherichia coli activates efficient and multiple site-specific nonstandard amino acid incorporation.ACS synthetic biology · 2014Article
- Expanding P450 catalytic reaction space through evolution and engineering.Current opinion in chemical biology · 2014Review
- Production of Fatty Acid-derived valuable chemicals in synthetic microbes.Frontiers in bioengineering and biotechnology · 2014Review
- The encapsulation of cell-free transcription and translation machinery in vesicles for the construction of cellular mimics.Journal of visualized experiments : JoVE · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Just as synthetic organic chemistry once revolutionized the ability of chemists to build molecules (including those that did not exist in nature) following a basic set of design rules, cell-free synthetic biology is beginning to provide an improved toolbox and faster process for not only harnessing but also expanding the chemistry of life. At the interface between chemistry and biology, research in cell-free synthetic systems is proceeding in two different directions: using synthetic biology for synthetic chemistry and using synthetic chemistry to reprogram or mimic biology. In the coming years, the impact of advances inspired by these approaches will make possible the synthesis of nonbiological polymers having new backbone compositions, new chemical properties, new structures, and new functions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.