Evidence map›Paper›PMID 22482996›Full record

ReviewJournal of natural products2012

Quantitative 1H NMR. Development and potential of an analytical method: an update.

Guido F Pauli, Tanja Gödecke, Birgit U Jaki, David C Lankin

Abstract readReview
In one paragraph

Review in Journal of natural products, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. QuantitativeMolecules (Basel, Switzerland) · 2026
    Review
  8. Article
  9. NMR-Based Quantification of Collagen Content in Protein Hydrolysates.Journal of agricultural and food chemistry · 2026
    Article
  10. Applications of quantitativeJournal of pharmaceutical analysis · 2026
    Review
  11. Article
  12. Article
  13. 1H NMR spectra as a characteristic of herbal preparations.Journal of food science and technology · 2025
    Article
  14. Polymorphism of PbActa crystallographica Section B, Structural science, crystal engineering and materials · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guido F PauliDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, USA. gfp@uic.edu
Tanja Gödecke
Birgit U Jaki
David C Lankin

Funding

Van Breemen: Project 3; Botanical Dietary Supplements - Metabolism and Safety in Women (Van Breemen)P50AT000155 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BOLTON, JUDY L · 1999 to 2019
$30.4M
Spectrometric Validation of Botanical Materials and Reference StandardsRC2AT005899 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PAULI, GUIDO F · 2009 to 2010
$1.2M
NCCIH NIH HHS P50 AT000155NCCIH NIH HHS RC2 AT005899
6 · The paper itself

Abstract

Covering the literature from mid-2004 until the end of 2011, this review continues a previous literature overview on quantitative (1)H NMR (qHNMR) methodology and its applications in the analysis of natural products. Among the foremost advantages of qHNMR is its accurate function with external calibration, the lack of any requirement for identical reference materials, a high precision and accuracy when properly validated, and an ability to quantitate multiple analytes simultaneously. As a result of the inclusion of over 170 new references, this updated review summarizes a wealth of detailed experiential evidence and newly developed methodology that supports qHNMR as a valuable and unbiased analytical tool for natural product and other areas of research.

Indexed as

Biological ProductsHumansMagnetic Resonance SpectroscopyMolecular StructureBiological Products

Identifiers

PMID22482996
PMCPMC3384681

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.