ArticleJournal of ophthalmology2012
Refractive Development in the "ROP Rat".
Article in Journal of ophthalmology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- A First-Passage Model of Intravitreal Drug Delivery and Residence Time-Influence of Ocular Geometry, Individual Variability, and Injection Location.Investigative ophthalmology & visual science · 2024Article
- In vivo MRI evaluation of early postnatal development in normal and impaired rat eyes.Scientific reports · 2021Article
- Refractive status and optical components of premature babies with or without retinopathy of prematurity at 7 years old.Translational pediatrics · 2020Article
- Effects of Hyperoxia on the Refraction in Murine Neonatal and Adult Models.International journal of molecular sciences · 2019Article
- The neural retina in retinopathy of prematurity.Progress in retinal and eye research · 2017Review
- Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine.Investigative ophthalmology & visual science · 2016Article
- Vulnerability of Dopaminergic Amacrine Cells to Chronic Ischemia in a Mouse Model of Oxygen-Induced Retinopathy.Investigative ophthalmology & visual science · 2016Article
- Retinal, visual, and refractive development in retinopathy of prematurity.Eye and brain · 2016Review
- Eye growth in term- and preterm-born eyes modeled from magnetic resonance images.Investigative ophthalmology & visual science · 2015Article
- Visually-driven ocular growth in mice requires functional rod photoreceptors.Investigative ophthalmology & visual science · 2014Article
- The rat with oxygen-induced retinopathy is myopic with low retinal dopamine.Investigative ophthalmology & visual science · 2013Article
- Development of a rat schematic eye from in vivo biometry and the correction of lateral magnification in SD-OCT imaging.Investigative ophthalmology & visual science · 2013Article
- Next-generation sequencing analysis of gene regulation in the rat model of retinopathy of prematurity.Documenta ophthalmologica. Advances in ophthalmology · 2013Article
- Alterations of the tunica vasculosa lentis in the rat model of retinopathy of prematurity.Documenta ophthalmologica. Advances in ophthalmology · 2013Article
- Retinal degeneration increases susceptibility to myopia in mice.Molecular vision · 2013Article
- Diminished vision in healthy aging is associated with increased retinal L-type voltage gated calcium channel ion influx.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Although retinopathy of prematurity (ROP) is clinically characterized by abnormal retinal vessels at the posterior pole of the eye, it is also commonly characterized by vascular abnormalities in the anterior segment, visual dysfunction which is based in retinal dysfunction, and, most commonly of all, arrested eye growth and high refractive error, particularly (and paradoxically) myopia. The oxygen-induced retinopathy rat model of ROP presents neurovascular outcomes similar to the human disease, although it is not yet known if the "ROP rat" also models the small-eyed myopia characteristic of ROP. In this study, magnetic resonance images (MRIs) of albino (Sprague-Dawley) and pigmented (Long-Evans) ROP rat eyes, and age- and strain-matched room-air-reared (RAR) controls, were examined. The positions and curvatures of the various optical media were measured and the refractive state (℞) of each eye estimated based on a previously published model. Even in adulthood (postnatal day 50), Sprague-Dawley and Long-Evans ROP rats were significantly myopic compared to strain-matched controls. The myopia in the Long-Evans ROP rats was more severe than in the Sprague-Dawley ROP rats, which also had significantly shorter axial lengths. These data reveal the ROP rat to be a novel and potentially informative approach to investigating physiological mechanisms in myopia in general and the myopia peculiar to ROP in particular.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.