ArticleThe Pediatric infectious disease journal2012
Neutrophil CD64 as a diagnostic marker in neonatal sepsis.
Article in The Pediatric infectious disease journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Diagnostic accuracy of interleukin-6 (IL-6) as a significant biomarker in late-onset neonatal sepsis: an updated systematic review and meta-analysis.European journal of pediatrics · 2025Pooled it
- Meta-analysis of diagnostic accuracy of neutrophil CD64 for neonatal sepsis.Italian journal of pediatrics · 2016Pooled it
- Diagnostic utility of neutrophil CD64 for early detection of neonatal sepsis in southwestern Nigeria: a comparative case-control study.BMC pediatrics · 2026Article
- Evaluation of whole blood CD64 for identifying infection in neonates receiving hospital care.Frontiers in immunology · 2025Article
- Developing Augmented Pro-SOFA and Pro-SAPS Models by Integrating Biomarkers PCT, NLR, and CRP with SOFA and SAPS-III Scores.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- The Neutrophil: Constant Defender and First Responder.Frontiers in immunology · 2020Review
- Neutrophil CD64 index in cerebrospinal fluid as a marker of bacterial ventriculitis in children with external ventricular drainage.BMC pediatrics · 2019Observational
- [CD64 index as a marker of infection in patients with postoperative fever].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2018Observational
- Decreased levels of regulatory B cells in patients with acute pancreatitis: association with the severity of the disease.Oncotarget · 2018Article
- Could Neutrophil CD64 Expression Be Used as a Diagnostic Parameter of Bacteremia in Patients with Febrile Neutropenia?Turkish journal of haematology : official journal of Turkish Society of Haematology · 2017Article
- Monocyte HLA-DR expression and neutrophil CD64 expression as biomarkers of infection in critically ill neonates and infants.Pediatric research · 2015Article
- Diagnostic value of blood gene expression signatures in active tuberculosis in Thais: a pilot study.Genes and immunity · 2015Article
- Neutrophil CD64 as a diagnostic marker of sepsis: impact on neonatal care.American journal of perinatology · 2015Article
- Role of Neutrophil CD64 Index as a Screening Marker for Late-Onset Sepsis in Very Low Birth Weight Infants.PloS one · 2015Article
- CD64 expression is increased in patients with severe acute pancreatitis: clinical significance.Gut and liver · 2014Article
- Time for a neonatal-specific consensus definition for sepsis.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2014Review
- Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease.Inflammatory bowel diseases · 2014Article
- Neonatal sepsis: an old problem with new insights.Virulence · 2014Review
- Diagnostic utility of neutrophil CD64 as a marker for early-onset sepsis in preterm neonates.PloS one · 2014Article
- CD64 as a potential biomarker in septic arthritis.BMC infectious diseases · 2013Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
We assessed neutrophil CD64 as a diagnostic marker for neonatal sepsis. For early-onset sepsis, the CD64 index with a cut-point value of 2.38 had sensitivity, specificity and negative predictive values of 100%, 68% and 100%, respectively. For late-onset sepsis, the respective values were 3.62, 75%, 77% and 96%. Neutrophil CD64 index can be incorporated as a valuable marker for excluding neonatal sepsis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.