Evidence map›Paper›PMID 22480467›Full record

ReviewThe Orthopedic clinics of North America2012

Structural and functional maturation of distal femoral cartilage and bone during postnatal development and growth in humans and mice.

Elaine F Chan, Ricky Harjanto, Hiroshi Asahara, Nozomu Inoue, Koichi Masuda, William D Bugbee, Gary S Firestein, Harish S Hosalkar, Martin K Lotz, Robert L Sah

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in The Orthopedic clinics of North America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Novel model for the induction of postnatal murine hip deformity.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019
    Article
  7. Article
  8. 3-dimensional metrics of proximal femoral shape deformities in Legg-Calvé-Perthes disease and slipped capital femoral epiphysis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018
    Article
  9. Article
  10. Unilateral heat accelerates bone elongation and lengthens extremities of growing mice.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2015
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Elaine F ChanDepartment of Bioengineering, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0412, USA.
Ricky Harjanto
Hiroshi Asahara
Nozomu Inoue
Koichi Masuda
William D Bugbee
Gary S Firestein
Harish S Hosalkar
Martin K Lotz
Robert L Sah
University of California, San Diego · USScripps Research Institute · USDoshisha University · JPRady Children's Hospital-San Diego · USScripps Clinic · US

Funding

TISSUE ACQUISITION, MORPHOLOGY, AND CELL CULTUREP01AG007996 · NIA · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI SAH, ROBERT L · 1989 to 2016
$26.0M
Developing Articular Cartilage: Function &RemodelingR01AR044058 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SAH, ROBERT L · 2000 to 2010
$3.3M
Mechanisms of Articular Cartilage LubricationR01AR051565 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SAH, ROBERT L · 2006 to 2010
$2.0M
Howard Hughes Medical InstituteNIAMS NIH HHS R01 AR044058NIAMS NIH HHS R01 AR051565NIA NIH HHS P01 AG007996
6 · The paper itself

Abstract

The size and shape of joints markedly affect their biomechanical properties, but the macroscopic 3-dimensional (3-D) mechanism and extent of cartilage and joint maturation during normal growth are largely unknown. This study qualitatively illustrates the development of the bone-cartilage interface in the knee during postnatal growth in humans and C57BL/6 wild-type mice, quantitatively defines the 3-D shape using statistical shape modeling, and assesses growth strain rates in the mouse distal femur. Accurate quantification of the cartilage-bone interface geometry is imperative for furthering the understanding of the macroscopic mechanisms of cartilage maturation and overall joint development.

Indexed as

Imaging, Three-DimensionalAnimalsAnimals, NewbornBody HeightBody WeightBone DevelopmentCartilage, ArticularChildChild, PreschoolFemurHumansImage Processing, Computer-AssistedInfantInfant, NewbornKnee JointMice

Identifiers

PMID22480467
PMCPMC3321216
OpenAlexW2071055496

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.