ArticlePloS one2012
Long-term mortality of patients with septic ocular or central nervous system complications from pyogenic liver abscess: a population-based study.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Critical Care Management Considerations inCase reports in critical care · 2026Article
- HypervirulentPharmaceuticals (Basel, Switzerland) · 2025Review
- Development and validation of a clinical-radiomics nomogram for the early prediction of Klebsiella pneumoniae liver abscess.Annals of medicine · 2024Article
- HypervirulentPathogens & immunity · 2024Review
- Literature- and Experience-Based Consensus for Acute Post-operative Endophthalmitis and Endogenous Endophthalmitis in Taiwan.Ophthalmology and therapy · 2024Article
- Microevolution of CG23-I Hypervirulent Klebsiella pneumoniae during Recurrent Infections in a Single Patient.Microbiology spectrum · 2022Article
- Metagenome Analysis of the Bacterial Characteristics in InvasiveFrontiers in cellular and infection microbiology · 2022Article
- Article
- Clinical features and development of Sepsis in Klebsiella pneumoniae infected liver abscess patients: a retrospective analysis of 135 cases.BMC infectious diseases · 2021Article
- Klebsiella pneumoniae-related invasive liver abscess syndrome complicated by purulent meningitis: a review of the literature and description of three cases.BMC infectious diseases · 2021Review
- Pyogenic Liver Abscess Risk in Patients With Newly Diagnosed Type 2 Diabetes Mellitus: A Nationwide, Population-Based Cohort Study.Frontiers in medicine · 2021Article
- Analysis of the clinical characteristics of 202 patients with liver abscess associated with diabetes mellitus and biliary tract disease.The Journal of international medical research · 2020Article
- Molecular and Clinical Characterization of Multidrug-Resistant and Hypervirulent Klebsiella pneumoniae Strains from Liver Abscess in Taiwan.Antimicrobial agents and chemotherapy · 2020Article
- Hypervirulent Klebsiella pneumoniae - clinical and molecular perspectives.Journal of internal medicine · 2020Review
- Hypervirulent Klebsiella pneumoniae.Clinical microbiology reviews · 2019Review
- Recent upper gastrointestinal panendoscopy increases the risk of pyogenic liver abscess.World journal of gastroenterology · 2017Article
- Pneumonia is an independent risk factor for pyogenic liver abscess: A population-based, nested, case-control study.PloS one · 2017Article
- Two unusual cases of successful treatment of hypermucoviscous Klebsiella pneumoniae invasive syndrome.BMC infectious diseases · 2016Article
- The emergence ofGut pathogens · 2016Article
- TREM-1 promotes survival during Klebsiella pneumoniae liver abscess in mice.Infection and immunity · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTaiwan is endemic for pyogenic liver abscess (PLA). Septic ocular or central nervous system (CNS) complications derived from PLA can result in catastrophic disability. We investigated the epidemiology and long-term prognosis of PLA patients with septic ocular or CNS complications over an 8-year period. METHODOLOGY/PRINCIPAL
findingsWe extracted 21,307 patients with newly diagnosed PLA from a nationwide health registry in Taiwan between 2000 and 2007. The frequency of and risk factors for PLA with septic ocular or CNS complications were determined. The 2-year survival of these patients was compared between those with and without septic ocular or CNS complications. Septic ocular or CNS complications accounted for 2.1% of all PLA patients. Age and the Charlson comorbidity index were significantly lower in PLA patients with ocular or CNS complications than those without. Diabetes and age <65 years were independent predictors of septic ocular or CNS complications. The 2-year mortality of patients with septic ocular or CNS complications was similar to those without complications (24.8% vs. 27.5%, p = 0.502). However, among patients <65 years old and a Charlson index ≤ 1, the 2-year mortality was significantly higher in those with than without complications (18.6% vs. 11.8%, p = 0.001). CONCLUSIONS/SIGNIFICANCE: Physicians should recognize that catastrophic disability due to ocular or neurological complications from PLA could lead to a poor long-term prognosis, and should follow-up these patients more closely.
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