ArticleThe Canadian journal of hospital pharmacy2010
Quality and usability of common drug information databases.
Article in The Canadian journal of hospital pharmacy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Drug interaction databases in medical literature: transparency of ownership, funding, classification algorithms, level of documentation, and staff qualifications. A systematic review.European journal of clinical pharmacology · 2015Pooled it
- User Beware: Inaccuracy and Inconsistency of Large Language Models in Providing Precision Dosing Recommendations for Patients With Kidney Impairment-A Case Series.Pharmacotherapy · 2026Article
- Evaluating NLP Approaches to Extract Drug Indications.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026Article
- An Integrated Approach for Representing Knowledge on the Potential of Drugs to Cause Acute Kidney Injury.Drug safety · 2025Article
- A common data model for the standardization of intensive care unit medication features.JAMIA open · 2024Article
- Medication patterns and dosing guidance in pediatric patients supported with intermittent hemodialysis or continuous kidney replacement therapy.Pediatric nephrology (Berlin, Germany) · 2024Review
- Article
- Intensive care drug therapy and its potential adverse effects on blood pressure and heart rate in critically ill children.World journal of pediatrics : WJP · 2023Article
- Evaluation of medication dose adjustments in patients with impaired renal function using different online drug information databases.European journal of hospital pharmacy : science and practice · 2022Observational
- Antimicrobial Dosing Recommendations in Pediatric Continuous Renal Replacement Therapy: A Critical Appraisal of Current Evidence.Frontiers in pediatrics · 2022Article
- A Comparison of Tertiary Drug Resources' Consistency Regarding Drug-Drug Interactions of Adjunctive Analgesics.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2021Article
- A Ten-year Report of Drug and Poison Information Center in Mashhad, Iran 2007-2017.Iranian journal of pharmaceutical research : IJPR · 2021Article
- Dosing Recommendations for Pediatric Patients With Renal Impairment.Journal of clinical pharmacology · 2020Article
- Evaluation of adverse drug reaction formatting in drug information databases.Journal of the Medical Library Association : JMLA · 2020Article
- Survey of Drug Information Database Preferences among Staff from Selected British Columbia Health Authorities.The Canadian journal of hospital pharmacy · 2020Article
- Adverse drug reactions in drug information databases: does presentation affect interpretation?Journal of the Medical Library Association : JMLA · 2020Article
- A comparison of the content and primary literature support for online medication information provided by Lexicomp and Wikipedia.Journal of the Medical Library Association : JMLA · 2018Article
- Review
- Analysis of reference sources used in drug-related Wikipedia articles.Journal of the Medical Library Association : JMLA · 2015Article
- Prevalence and Predictors of Important Telaprevir Drug Interactions Among Patients Coinfected With Hepatitis C and Human Immunodeficiency Virus.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPharmacists' access to user-friendly electronic drug information databases that can quickly provide accurate, up-to-date information has become increasingly important. Unfortunately, decisions about purchasing subscriptions to such services are not always made objectively. Previously published studies have compared drug information databases, but there are no recent analyses from the perspective of Canadian hospital pharmacists.
objectiveTo determine overall preferences among the most commonly used online drug information databases, based on an appraisal of the quality, performance, and usability of the databases and users' preferences.
methodsQualitative and quantitative analyses with descriptive and inferential statistics were used to compare the Clinical Pharmacology, Lexi-Comp Online, and Micromedex databases. Quality scores were determined from investigators' consensus ratings across 5 categories of quality indicators. Performance scores were determined according to the ability of a database to answer 15 clinical drug information questions. Usability scores were determined from user ratings in 7 domains. Users' preferences were assessed through rankings of the databases by 26 practising pharmacists.
resultsThe highest quality and performance scores were awarded to Lexi-Comp Online, whereas Micromedex received the lowest overall usability score, attributable to poor scores for layout, navigation, and speed. Lack of Canadian content was identified as a major disadvantage of the Clinical Pharmacology database. Users ranked Micromedex significantly lower than the other databases, whereas the majority of users ranked Lexi-Comp Online as the most preferred database.
conclusionsLexi-Comp Online appeared to be the most preferred database, whereas Micromedex was clearly the least preferred database. These findings should be considered in future decisions about purchasing database subscriptions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.