ReviewPlant foods for human nutrition (Dordrecht, Netherlands)2012
Mitigation of obesity-promoted diseases by Nigella sativa and thymoquinone.
Review in Plant foods for human nutrition (Dordrecht, Netherlands), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 34 citations in OpenAlex.
- Phytochemicals and Irisin as Multi-Target Regulators of Adipose Tissue Browning and Metabolic Reprogramming: Synergies with GLP-1 Pathways.Antioxidants (Basel, Switzerland) · 2026Review
- The effect ofJournal of diabetes and metabolic disorders · 2022Article
- Comparative Analysis of the Efficiency of Medicinal Plants for the Treatment and Prevention of COVID-19.International journal of biomaterials · 2022Review
- The effect of hydroalcoholic extract ofInternational journal of reproductive biomedicine · 2021Article
- An updated knowledge of Black seed (Journal of herbal medicine · 2021Review
- Regulation of alternative splicing in obesity-induced hypertension.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Crocin prevents haloperidol-induced orofacial dyskinesia: possible an antioxidant mechanism.Iranian journal of basic medical sciences · 2016Article
- An Evaluation of the Protective Effects of Thymoquinone on Amikacin-Induced Ototoxicity in Rats.Clinical and experimental otorhinolaryngology · 2015Article
- A review of the effects of Nigella sativa L. and its constituent, thymoquinone, in metabolic syndrome.Journal of endocrinological investigation · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is closely associated with increased incidence of cardiovascular diseases, cancer, insulin resistance, and immune dysfunction, and thus obesity-mitigation strategies should take into account these secondary pathologies in addition to promoting weight loss. Recent studies indicate that black cumin (Nigella sativa) has cardio-protective, anti-cancer, anti-diabetic, antioxidant, and immune-modulatory properties. While black cumin and/or its major bioactive constituent, thymoquinone have demonstrated bioactivity in a variety of disease models, the mechanisms of action are largely unknown. Given the growing interest in and the use of functional foods and nutraceuticals, as well as the increase in obesity and chronic diseases worldwide, further research into the therapeutic/preventive effects of black cumin may be beneficial.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.