Evidence map›Paper›PMID 22477060›Full record

ArticleJournal of fluorescence2012

Investigations on photoinduced interaction of 9-aminoacridine with certain catechols and rutin.

C Manivannan, K Meenakshi Sundaram, R Renganathan, M Sundararaman

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 12 citations in OpenAlex.

  1. Effects of rutin on acrylamide-induced neurotoxicity.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

C ManivannanSchool of Chemistry, Bharathidasan University, Tiruchirappalli-620 024, Tamil Nadu, India.
K Meenakshi Sundaram
R Renganathan
M Sundararaman
Bharathidasan University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fluorescence quenching of 9-aminoacridine by certain biologically important catechols and rutin was investigated using absorption, steady state and time resolved fluorescence measurements. The in vitro-antioxidant activities of the above compounds were studied using deoxyribose degradation assay and nitric oxide scavenging assay. The experimental results showed that the fluorescence of 9-aminoacridine was quenched by quencher molecules via forming ground state complex. The bimolecular quenching rate constant k(q), binding constant (K) and number of binding sites (n) were calculated at different temperatures from relevant fluorescence data. Static quenching mechanism was supported by lifetime measurement. The free energy change (ΔG(et)) for electron transfer process was calculated by Rehm-Weller equation. The binding distance of 4-nitrocatechol with 9-aminoacridine was obtained according to Forster's non-radiative energy transfer theory. Nature of binding forces and their interactions was probed based on thermodynamic parameters.

Indexed as

Photochemical ProcessesAminacrineBinding SitesCatecholsDeoxyriboseDopamineElectrochemistryEnergy TransferFree Radical ScavengersLevodopaNitric OxideOxidation-ReductionRutinSolventsSpectrometry, FluorescenceAminacrinecatecholCatecholsDeoxyriboseDopamineFree Radical ScavengersLevodopaNitric OxideRutinSolvents

Identifiers

PMID22477060
OpenAlexW2091584552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.