ArticleYonsei medical journal2012
Phagocytosis and endocytosis of silver nanoparticles induce interleukin-8 production in human macrophages.
Article in Yonsei medical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 61 citations in OpenAlex.
- Oxidative stress-driven disease-associated microglia (DAM)-like polarization in human microglia (HMC3) cells exposed to small-size silver nanoparticles in a transwell co-culture system with neurons (cholinergic differentiated SH-SY5Y) cells in vitro.Archives of toxicology · 2026Article
- Unlocking the Potential of Silver Nanoparticles: From Synthesis to Versatile Bio-Applications.Pharmaceutics · 2024Review
- Pro-inflammatory effects of silver nanoparticles in the intestine.Archives of toxicology · 2022Review
- Cancer Therapy by Silver Nanoparticles: Fiction or Reality?International journal of molecular sciences · 2022Review
- Implementation of a Dynamic Co-Culture Model Abated Silver Nanoparticle Interactions and Nanotoxicological Outcomes In Vitro.Nanomaterials (Basel, Switzerland) · 2021Article
- Novel elvitegravir nanoformulation for drug delivery across the blood-brain barrier to achieve HIV-1 suppression in the CNS macrophages.Scientific reports · 2020Article
- Antiviral and Immunomodulatory Activity of Silver Nanoparticles in Experimental RSV Infection.Viruses · 2019Article
- Food additives can act as triggering factors in celiac disease: Current knowledge based on a critical review of the literature.World journal of clinical cases · 2019Review
- Metal Organic Framework (MOF) Particles as Potential Bacteria-Mimicking Delivery Systems for Infectious Diseases: Characterization and Cellular Internalization in Alveolar Macrophages.Pharmaceutical research · 2019Article
- One-pot green synthesis and structural characterisation of silver nanoparticles using aqueous leaves extract ofIET nanobiotechnology · 2018Article
- Gold Nanoparticles in Single-Cell Analysis for Surface Enhanced Raman Scattering.Molecules (Basel, Switzerland) · 2016Review
- Intracellular trafficking pathways in silver nanoparticle uptake and toxicity in Caenorhabditis elegans.Nanotoxicology · 2016Article
- Nanosized silver (II) pyridoxine complex to cause greater inflammatory response and less cytotoxicity to RAW264.7 macrophage cells.Nanoscale research letters · 2015Article
- Cytotoxic and proinflammatory effects of PVP-coated silver nanoparticles after intratracheal instillation in rats.Beilstein journal of nanotechnology · 2013Article
- The effects of silica nanoparticles in macrophage cells.Immune network · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phagocytosis or endocytosis by macrophages is critical to the uptake of fine particles, including nanoparticles, in order to initiate toxic effects in cells. Here, our data enhance the understanding of the process of internalization of silver nanoparticles by macrophages. When macrophages were pre-treated with inhibitors to phagocytosis, caveolin-mediated endocytosis, or clathrin-mediated endocytosis, prior to exposure to silver nanoparticles, Interleukin-8 (IL-8) production was inhibited. Although cell death was not reduced, the inflammatory response by macrophages was compromised by phagocytosis and endocytosis inhibitors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.