Evidence map›Paper›PMID 22476947›Full record

ReviewDiabetologia2012

Diabetes and cancer (1): evaluating the temporal relationship between type 2 diabetes and cancer incidence.

J A Johnson, B Carstensen, D Witte, S L Bowker, L Lipscombe, A G Renehan, Diabetes and Cancer Research Consortium

Abstract readReview
PubMed Publisher
In one paragraph

Review in Diabetologia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  11. Use of thiazolidinediones and the risk of bladder cancer among people with type 2 diabetes: a meta-analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2012
    Pooled it
  12. Article
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  14. Review
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  19. Obesity and its management in primary care setting.Journal of diabetes and its complications · 2025
    Review
  20. Article

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

J A JohnsonSchool of Public Health, University of Alberta, 2040 Li Ka Shing Center, Edmonton, AB, Canada T6G 2E1. jeff.johnson@ualberta.ca
B Carstensen
D Witte
S L Bowker
L Lipscombe
A G Renehan
Diabetes and Cancer Research Consortium

Funding

Canadian Institutes of Health Research MOP-82737
6 · The paper itself

Abstract

Substantial evidence suggests that people with type 2 diabetes have an increased risk of developing several types of cancers. These associations may be due to a number of direct and indirect mechanisms. Observational studies of these associations, including the potential role for glucose-lowering therapy, are being increasingly reported, but face a number of methodological challenges. This paper is the first of two review papers addressing methodological aspects underpinning the interpretations of links between diabetes and cancer, and suggests potential approaches to study designs to be considered in observational studies. This paper reviews factors related to cancer incidence in the diabetic population; the second paper relates to studies of cancer mortality.

Indexed as

Diabetes Mellitus, Type 2HumansNeoplasmsRisk Factors

Identifiers

PMID22476947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.