ArticleFolia microbiologica2012
Cytokine expression in the colostral cells of healthy and allergic mothers.
Article in Folia microbiologica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- The impact of environmental pollution on the quality of mother's milk.Environmental science and pollution research international · 2019Pooled it
- Review
- Maternal and Neonatal Factors Modulating Breast Milk Cytokines in the First Month of Lactation.Antioxidants (Basel, Switzerland) · 2023Article
- Association of Severe Bronchiolitis during Infancy with Childhood Asthma Development: An Analysis of the ECHO Consortium.Biomedicines · 2022Article
- Effect of early postnatal supplementation of newborns with probiotic strainFrontiers in immunology · 2022Article
- Immunomodulatory Effects of Human Colostrum and Milk.Pediatric gastroenterology, hepatology & nutrition · 2021Review
- Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination.International journal of molecular sciences · 2021Review
- Microbiota Alters Urinary Bladder Weight and Gene Expression.Microorganisms · 2020Article
- Review
- Article
- The effect of the colostral cells on gene expression of cytokines in cord blood cells.Folia microbiologica · 2017Article
- Human milk composition: nutrients and bioactive factors.Pediatric clinics of North America · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is no doubt about the beneficial effect of breastfeeding on the newborn's immune system. It is not fully elucidated what the differences are between the colostrum/milk of healthy and allergic mothers and how beneficial breastfeeding by an allergic mother is. The gene expression of selected cytokines was tested in cells isolated from colostra of healthy and allergic mothers using quantitative real-time PCR. Allergic phenotype was evident in colostral cells of allergic mothers: gene expressions of IL-4, IL-13 and EGF were increased and those of IFN-gamma decreased in comparison with colostral cells of healthy mothers. The allergic phenotype of the colostral cells of allergic mothers supporting the bias to a Th2 type response was found. It remains a question if a small number of these cells could influence the immature newborn immune system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.