ArticleJournal of the Association for Research in Otolaryngology : JARO2012
Maturation and aging of the human cochlea: a view through the DPOAE looking glass.
Article in Journal of the Association for Research in Otolaryngology : JARO, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 77 citations in OpenAlex.
- Estrogen deficiency and risk of hearing loss in pediatric Turner syndrome.The Journal of clinical investigation · 2026Trial
- Hearing Characteristics of Adults before Exposure to Potentially Ototoxic Chemotherapy.International archives of otorhinolaryngology · 2026Article
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- Sources of Microstructure in Mammalian Cochlear Responses.Journal of the Association for Research in Otolaryngology : JARO · 2025Review
- Article
- Detection of mild sensory hearing loss using a joint reflection-distortion otoacoustic emission profile.The Journal of the Acoustical Society of America · 2024Article
- Female GluA3-KO mice show early onset hearing loss and afferent swellings in ambient sound levels.bioRxiv : the preprint server for biology · 2024Article
- Swept Along: Measuring Otoacoustic Emissions Using Continuously Varying Stimuli.Journal of the Association for Research in Otolaryngology : JARO · 2024Review
- Heightened OAEs in young adult musicians: Influence of current noise exposure and training recency.Hearing research · 2024Article
- Descriptive Characterization of High-Frequency Distortion Product Otoacoustic Emission Source Components in Children.Journal of speech, language, and hearing research : JSLHR · 2023Article
- Noise-Induced Hearing Loss.Journal of clinical medicine · 2023Review
- Middle ear muscle and medial olivocochlear activity inferred from individual human ears via cochlear potentials.The Journal of the Acoustical Society of America · 2023Article
- Subclinical Hearing Deficits in Noise-Exposed Firefighters.International journal of environmental research and public health · 2022Article
- The influence of self-reported noise exposure on 2ƒThe Journal of the Acoustical Society of America · 2022Article
- Distortion Product Otoacoustic Emission (DPOAE) Growth in Aging Ears with Clinically Normal Behavioral Thresholds.Journal of the Association for Research in Otolaryngology : JARO · 2021Article
- Cochlear tuning estimates from level ratio functions of distortion product otoacoustic emissions.International journal of audiology · 2021Article
- Peripheral deficits and phase-locking declines in aging adults.Hearing research · 2021Article
- High-Frequency Cochlear Amplifier Dysfunction: A Dominating Contribution to the Cognitive-Ear Link.Frontiers in aging neuroscience · 2021Article
- The effects of aging on peripheral and central auditory function in adults with normal hearing.American journal of translational research · 2021Article
- Extended low-frequency phase of the distortion-product otoacoustic emission in human newborns.JASA express letters · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Cochlear function changes throughout the human lifespan. Distortion product otoacoustic emissions (DPOAEs) were recorded in 156 ears to examine these changes and speculate as to their mechanistic underpinnings. DPOAEs were analyzed within the context of current OAE generation theory, which recognizes distinct emission mechanisms. Seven age groups including premature newborns through senescent adults were tested with a swept-tone DPOAE protocol to examine magnitude and phase features of both the mixed DPOAE and individual distortion and reflection components. Results indicate (1) 6-8-month-old infants have the most robust DPOAE and component levels for frequencies >1.5 kHz; (2) older adults show a substantial reduction in DPOAE and distortion-component levels combined with a smaller drop in reflection-component levels; (3) all age groups manifest a violation of distortion phase invariance at frequencies below 1.5 kHz consistent with a secular break in cochlear scaling; the apical phase delay is markedly longer in newborns; and (4) phase slope of reflection emissions is most shallow in the older adults. Combined findings suggest that basilar membrane motion in the apical half of the cochlea is immature at birth and that the cochlea of senescent adults shows reduced nonlinearity and relatively shallow reflection-component phase slope, which can be interpreted to suggest degraded tuning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.