ArticleJournal of neuro-oncology2012
FABP4 is a candidate marker of cerebellar liponeurocytomas.
Article in Journal of neuro-oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Stereotactic radiosurgery for progression of cerebellar liponeurocytoma after resection: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Dysregulated lipid metabolism and hypomyelination in postnatal peroxisome-deficientFrontiers in molecular neuroscience · 2026Article
- Cerebellar liponeurocytoma: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Surgical management and clinical outcomes of cerebellar liponeurocytomas-a report of seven cases and a pooled analysis of individual patient data.Neurosurgical review · 2022Article
- A case of adult cerebellar liponeurocytoma with atypical radiological features and long survival with literature review.Radiology case reports · 2022Article
- Recurrent liponeurocytoma: A case report and systematic review of the literature.Surgical neurology international · 2022Review
- Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review.Frontiers in oncology · 2021Article
- Supratentorial intracerebral cerebellar liponeurocytoma: A case report and literature review.Medicine · 2018Review
- Article
- Cerebellar liponeurocytoma: A case report and review of the literature.Oncology letters · 2016Article
- Understanding cerebellar liponeurocytomas: case report and literature review.Case reports in neurological medicine · 2014Article
- IL-1β, RAGE and FABP4: targeting the dynamic trio in metabolic inflammation and related pathologies.Future medicinal chemistry · 2013Article
- Multifocal cerebellar liponeurocytoma: How to deal with it?Journal of neurosciences in rural practiceArticle
- Cerebellar Liponeurocytoma: A Rare Fatty Tumor and its Literature Review.Journal of neurosciences in rural practiceArticle
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebellar liponeurocytoma (cLPN) is a very rare central nervous system (CNS) tumour recently recognized as a clinical and pathological entity distinct from medulloblastoma (MB), and included in the WHO classification of CNS tumours under the heading "glioneuronal tumours". cLPN typically develop in adult age and have a favourable prognosis compared with MB. In this work, we reviewed the clinical and neuroradiological data of two novel cases of adult cLPN diagnosed at our institution; one patient developed distant metastases. We tried to identify novel molecular markers for this malignancy. We found that the transcription factor NEUROG1 (but not ATOH1) is expressed in cLPN, unlike normal adult cerebellum, and that fatty acid binding protein 4 (FABP4), typically found in adipocytes, is significantly overexpressed compared with both normal adult cerebellum and human MB. These findings suggest cLPN occur as a result of transformation of cerebellar progenitors, which are distinct from cerebellar granule progenitors, and aberrantly differentiate into adipocyte-like tumour cells. They also suggest that analysis of FABP4 expression is of help to differentiate cLPN from MB.
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