Evidence map›Paper›PMID 22476605›Full record

ReviewPediatric cardiology2012

The Ross classification for heart failure in children after 25 years: a review and an age-stratified revision.

Robert D Ross

3 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 73 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02652676 naterminatednot on this mapstarted 2016, after this paper: background citation

Reversible Pulmonary Artery Banding as Simplified Management of End-stage Dilated Left Ventriculopathy in Early Life

TypeinterventionalSponsorLoma Linda UniversityRan2016 to 2021Enrolled4ConditionsAcute on Chronic Systolic Congestive Heart FailureArmsReversible Pulmonary Artery Banding, GORE-TEX DualMesh EMERGE PLUS Biomaterial
NCT03885050 unknown statusnot on this mapstarted 2019, after this paper: background citation

Modified Ross Score for Evaluation of Heart Failure in Children With Lower Respiratory Tract

TypeobservationalSponsorAssiut UniversityRan2019 to 2020Enrolled100ConditionsHeart FailureArmsRoss score
NCT04162444 recruitingnot on this mapstarted 2020, after this paper: background citation

Short-term and Midterm Results of the Aortic Valve Reconstruction With Autopericardium in Children

TypeobservationalSponsorNational Medical Research Center for Children's Health, Russian FederationRan2020 to 2027Enrolled40ConditionsAortic Valve InsufficiencyArmsPhysical examination, The Ross Classification for Heart Failure in Children, The Aristotle score, Assessment of administered specific therapy, Multispiral computed tomography/3D echocardiography
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Long-term surgical outcomes of congenital supravalvular aortic stenosis: a systematic review, meta-analysis and microsimulation study.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024
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  10. Clinical course of severe congenital aortic valve stenosis in children.International journal of cardiology. Congenital heart disease · 2025
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Robert D RossDivision of Pediatric Cardiology, Carmen and Ann Adams, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, 3901 Beaubien Blvd., Detroit, MI, 48201, USA. rross@dmc.org

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate grading of the presence and severity of heart failure (HF) signs and symptoms in infants and children remains challenging. It has been 25 years since the Ross classification was first used for this purpose. Since then, several modifications of the system have been used and others proposed. New evidence has shown that in addition to signs and symptoms, data from echocardiography, exercise testing, and biomarkers such as N-terminal pro-brain natriuretic peptide (NT-proBNP) all are useful in stratifying outcomes for children with HF. It also is apparent that grading of signs and symptoms in children is dependent on age because infants manifest HF differently than toddlers and older children. This review culminates in a proposed new age-based Ross classification for HF in children that incorporates the most useful data from the last two decades. Testing of this new system will be important to determine whether an age-stratified scoring system can unify the way communication of HF severity and research on HF in children is performed in the future.

Indexed as

AdolescentAge FactorsBiomarkersChildChild, PreschoolFemaleHeart FailureHeart Function TestsHumansInfantInfant, NewbornMaleRespiratory Function TestsSeverity of Illness IndexBiomarkers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.