Evidence map›Paper›PMID 22476539›Full record

ArticleLab on a chip2012

Quantitative modeling of the behaviour of microfluidic autoregulatory devices.

Hyun-Joo Chang, Wubing Ye, Emil P Kartalov

Abstract read
In one paragraph

Article in Lab on a chip, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Exploiting Device Deformability for Fluid and Particle Manipulation.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  3. Review
  4. Article
  5. Modular microfluidics for life sciences.Journal of nanobiotechnology · 2023
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hyun-Joo ChangDept. of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90089-9092, USA. hyunjoo@usc.edu
Wubing Ye
Emil P Kartalov

Funding

Integrated Nanofluidic BioMEMS for Biomedical Diagnostics and AnalysisR00EB007151 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KARTALOV, EMIL P · 2008 to 2010
$737k
NIBIB NIH HHS 4R00EB007151NIBIB NIH HHS R00 EB007151
6 · The paper itself

Abstract

We develop a theoretical model for a fluidic current source consisting of a via, a detour channel, and a push-up type micro-valve. The model accurately describes the non-linear behaviour of this type of device, which has been previously measured experimentally. We show how various structural parameters and material properties of the device influence the saturated flow rate and the minimum driving pressure required for the device to function as a current source. Conversely, the model can be used to design a fluidic current source with a desired saturated flow rate and low operational pressure. The present model can be straightforwardly applied to microfluidic circuits composed of many functional autoregulatory devices.

Indexed as

Models, TheoreticalDimethylpolysiloxanesMicrofluidic Analytical TechniquesMicrofluidicsNylonsPressureDimethylpolysiloxanesNylonspoly(dimethylsiloxane)-polyamide copolymer

Identifiers

PMID22476539
PMCPMC3375392

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.