Evidence map›Paper›PMID 22476503›Full record

ArticleJournal of assisted reproduction and genetics2012

In-vitro maturation of human oocytes: before or after vitrification?

Giovanna Fasano, Isabelle Demeestere, Yvon Englert

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Fertility preservation strategies for cancerous women: An updated review.Turkish journal of obstetrics and gynecology · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. [Causes of oocyte vitrification and its value in assisted reproductive technology].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019
    Article
  12. Article
  13. Immature Oocyte for Fertility Preservation.Frontiers in endocrinology · 2019
    Review
  14. Article
  15. OocyteTurkish journal of obstetrics and gynecology · 2018
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giovanna FasanoResearch Laboratory on Human Reproduction, Medicine Faculty, Université Libre de Bruxelles, Belgium, Campus Erasme, Brussels, Belgium. Giovanna.Fasano@erasme.ulb.ac.be
Isabelle Demeestere
Yvon Englert

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to determine if in-vitro maturation (IVM) of human immature oocytes should be performed before or after vitrification.

methodsA total of 184 immature oocytes were randomly divided into two different groups: 100 were vitrified at metaphase II (MII) stage 24 h-48 h after IVM (group 1) and 84 were immediately vitrified at germinal vesicle (GV) or metaphase I (MI) stages and in vitro matured after warming (group 2).

resultsSurvival rate after warming was similar in both groups (86.9% versus 84.5%). However, oocyte maturation rate per collected oocyte was significantly higher for oocytes matured before vitrification (group 1, 46%) than for oocytes vitrified before IVM (group 2, 23.8%) (p < 0.01). Consequently, the number of MII oocytes inseminated per oocyte collected was significantly higher for group 1 (40%) than for group 2 (23.8%) (p < 0.05).

conclusionIVM procedure is more efficient when it is performed before oocyte vitrification.

Indexed as

VitrificationBlastocystCells, CulturedCell SurvivalCryopreservationFemaleFertilization in VitroHumansMetaphaseOocytes

Identifiers

PMID22476503
PMCPMC3370053

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.