SynthesisIntensive care medicine2012
Does patient volume affect clinical outcomes in adult intensive care units?
Synthesis in Intensive care medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- The Volume-Outcome Relationship in Critical Care: A Systematic Review and Meta-analysis.Chest · 2015Pooled it
- Impact of hospital sepsis case volume on mortality in sepsis patients: a meta-analysis.Frontiers in medicine · 2026Review
- Early predictors of unfavorable outcomes in pediatric acute respiratory failure.Journal of intensive care · 2024Article
- Impact of institutional case volume on intensive care unit mortality.Acute and critical care · 2023Article
- Protocol for the development of a core outcome set for studies on centralisation of healthcare services.BMJ open · 2023Article
- The effect of minimum volume standards in hospitals (MIVOS) - protocol of a systematic review.Systematic reviews · 2023Article
- Are patient volume and care level in teaching hospitals variables affecting clinical outcomes in adult intensive care units?Einstein (Sao Paulo, Brazil) · 2023Article
- Effect of Institutional Case Volume on In-Hospital and Long-Term Mortality in Critically Ill Patients Requiring Mechanical Ventilation for 48 Hours or More.Journal of Korean medical science · 2019Article
- The Association Between Acute Respiratory Distress Syndrome Hospital Case Volume and Mortality in a U.S. Cohort, 2002-2011.Critical care medicine · 2018Article
- Hospital-Level Changes in Adult ICU Bed Supply in the United States.Critical care medicine · 2017Article
- Article
- PICU Volume and Outcome: A Severity-Adjusted Analysis.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2016Article
- Does intermediate care improve patient outcomes or reduce costs?Critical care (London, England) · 2015Review
- The association between ICU level of care and mortality in the Netherlands.Intensive care medicine · 2015Article
- Effect of cardiogenic shock hospital volume on mortality in patients with cardiogenic shock.Journal of the American Heart Association · 2015Article
- Hospital mortality of adults admitted to Intensive Care Units in hospitals with and without Intermediate Care Units: a multicentre European cohort study.Critical care (London, England) · 2014Observational
- Intensive care medicine is 60 years old: the history and future of the intensive care unit.Clinical medicine (London, England) · 2014Article
- Should mechanical ventilation care be centralized and should we thus transfer all ventilated patients to high volume units? Take a breath first.Intensive care medicine · 2014Article
- What's new in ICU volume-outcome relationships?Intensive care medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis systematic review assessed if outcomes in adult intensive care units (ICUs) are related to hospital and ICU patient volume.
methodsA systematic search strategy was used to identify studies reporting on volume-outcome relationship in adult ICU patients till November 2010. Inclusion of articles was established through a predetermined protocol. Two reviewers assessed studies independently and data extraction was performed using standardized data extraction forms.
resultsA total of 254 articles were screened. Of these 25 were relevant to this study. After further evaluation a total of 13 studies including 596,259 patients across 1,068 ICUs met the inclusion criteria and were reviewed. All were observational cohort studies. Four of the studies included all admissions to ICU, five included mechanically ventilated patients, two reported on patients admitted with sepsis and one study each reported on patients admitted with medical diagnoses and post cardiac arrest patients admitted to ICU, respectively. There was a wide variability in the quantitative definition of volume and classification of hospitals and ICUs on this basis. Methodological heterogeneity amongst the studies precluded a formal meta-analysis. A trend towards favourable outcomes for high volume centres was observed in all studies. Risk-adjusted mortality rates revealed a survival advantage for a specific group of patients in high volume centres in ten studies but no significant difference in outcomes was evident in three studies.
conclusionsThe results indicate that outcomes of certain subsets of ICU patients--especially those on mechanical ventilation, high-risk patients, and patients with severe sepsis--are better in high volume centres within the constraints of risk adjustments.
Indexed as
Identifiers
22476446What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.