ArticlePlanta2012
Narciclasine inhibits the responses of Arabidopsis roots to auxin.
Article in Planta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- The Phytotoxin Myrigalone A Triggers a Phased Detoxification Programme and InhibitsInternational journal of molecular sciences · 2022Article
- The Steroid Saponin Protodioscin ModulatesPlants (Basel, Switzerland) · 2021Article
- Coumarin Interferes with Polar Auxin Transport Altering Microtubule Cortical Array Organization inInternational journal of molecular sciences · 2021Article
- Transcriptome Analysis of a Premature Leaf Senescence Mutant of Common Wheat (Triticum aestivum L.).International journal of molecular sciences · 2018Article
- Transcriptomic analysis reveals key early events of narciclasine signaling in Arabidopsis root apex.Plant cell reports · 2016Article
- The Allelochemical MDCA Inhibits Lignification and Affects Auxin Homeostasis.Plant physiology · 2016Article
- Calcium alleviates cadmium-induced inhibition on root growth by maintaining auxin homeostasis in Arabidopsis seedlings.Protoplasma · 2016Article
- Article
- Cyclic GMP is involved in auxin signalling during Arabidopsis root growth and development.Journal of experimental botany · 2014Article
- Towards a molecular understanding of the biosynthesis of amaryllidaceae alkaloids in support of their expanding medical use.International journal of molecular sciences · 2013Review
- The use of bio-guided fractionation to explore the use of leftover biomass in Dutch flower bulb production as allelochemicals against weeds.Molecules (Basel, Switzerland) · 2013Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plant hormone auxin plays a central role in the regulation of plant growth and development, as well as in responses to environmental stimuli. Narciclasine (NCS, an Amaryllidaceae alkaloid) isolated from Narcissus tazetta bulbs has a broad range of inhibitory effects on plants. In this study, the role of NCS in responses to auxin in Arabidopsis thaliana roots was investigated. We demonstrated the inhibitory effects of NCS on auxin-inducible lateral root formation, root hair formation, primary root growth, and the expression of primary auxin-inducible genes in Arabidopsis roots using DR5::GUS reporter gene, native auxin promoters (IAA12::GUS, IAA13::GUS), and quantitative reverse transcription PCR analysis. Results also showed that NCS did not affect the expression of cytokinin-inducible ARR5::GUS reporter gene. NCS relieved the auxin-enhanced degradation of the Aux/IAA repressor modulated by the SCFTIR1 ubiquitin-proteasome pathway. In addition, NCS did not alter the auxin-stimulated interaction between IAA7/AXR2 (Aux/IAA proteins) and the F-box protein TIR1 activity of the proteasome. Taken together, these results suggest that NCS acts on the auxin signaling pathway upstream of TIR1, which modulates Aux/IAA protein degradation, and thereby affects the auxin-mediated responses in Arabidopsis roots.
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