Evidence map›Paper›PMID 22476252›Full record

SynthesisPediatric nephrology (Berlin, Germany)2013

The contribution of systematic reviews to the practice of pediatric nephrology.

Elisabeth Hodson, Jonathan C Craig

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Pediatric nephrology (Berlin, Germany), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elisabeth HodsonCentre for Kidney Research, The Children's Hospital at Westmead, Westmead, Sydney, Australia. elisabeth.hodson@health.nsw.gov.au
Jonathan C Craig

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The key to accurate decision-making is to use the best available evidence. Systematic reviews aim to identify and combine evidence using systematic methods to minimize bias to provide reliable data for patient care. While systematic reviews can address different clinical questions, the methodology is most developed for systematic reviews of randomized controlled trials. Such systematic reviews include all available trial evidence, enhance the precision of the estimates of treatment effects, and identify where evidence is lacking or where sufficient evidence is already available. However the term "systematic review" does not guarantee that a review covers all the available data, that the validity of included studies has been appropriately assessed, or that data have been combined appropriately in meta-analyses. Biases in systematic review include those related to identifying data (publication bias, language bias, selective reporting of outcomes) and those due to the design and conduct of trials (selection bias, performance bias, detection bias, attrition bias). Thus, readers should read a systematic review carefully before accepting its results and conclusions. This review examines the information that can be provided by systematic reviews of randomized controlled trials together with the biases that can potentially jeopardize the results and conclusions.

Indexed as

NephrologyPediatricsReview Literature as TopicEvidence-Based MedicineHumansMeta-Analysis as TopicPublication BiasSelection Bias

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.