Evidence map›Paper›PMID 22475340›Full record

ArticleJournal of medical case reports2012

Acute tubulointerstitial nephritis complicating Legionnaires' disease: a case report.

Aurélie Daumas, Fadwa El-Mekaoui, Stanislas Bataille, Laurent Daniel, Jean-Marie Caporossi, Pierre-Edouard Fournier, Stéphane Burtey, Bertrand Dussol, Yvon Berland, Noémie Jourde-Chiche

Open access · goldAbstract read
In one paragraph

Article in Journal of medical case reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Aurélie DaumasService de Néphrologie, Dialyse et Transplantation rénale, Assistance Publique des Hôpitaux de Marseille (AP-HM), Hôpital de la Conception, Bd Baille, F-13005 Marseille, France. Aurelie.DAUMAS@ap-hm.fr.
Fadwa El-Mekaoui
Stanislas Bataille
Laurent Daniel
Jean-Marie Caporossi
Pierre-Edouard Fournier
Stéphane Burtey
Bertrand Dussol
Yvon Berland
Noémie Jourde-Chiche
Hôpital de la Conception · FRHôpital de la Timone · FRInstitut de Recherche pour le Développement · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLegionnaires' disease is recognized as a multi-systemic illness. Afflicted patients may have pulmonary, renal, gastrointestinal tract and central nervous system complications. However, renal insufficiency is uncommon. The spectrum of renal involvement may range from a mild and transient elevation of serum creatinine levels to anuric renal failure requiring dialysis and may be linked to several causes. In our present case report, we would like to draw attention to the importance of the pathological documentation of acute renal failure by reporting a case of a patient with acute tubulointerstitial nephritis complicating Legionnaires' disease. CASE PRESENTATION: A 55-year-old Caucasian man was admitted to our hospital for community-acquired pneumonia complicated by acute renal failure. Legionella pneumophila serogroup type 1 was diagnosed. Although the patient's respiratory illness responded to intravenous erythromycin and ofloxacin therapy, his renal failure worsened, he became anuric, and hemodialysis was started. A renal biopsy was performed, which revealed severe tubulointerstitial nephritis. After initiation of steroid therapy, his renal function improved dramatically.

conclusionsThis case highlights the importance of kidney biopsies in cases where acute renal failure is a complicating factor in Legionnaires' disease. If the presence of acute tubulointerstitial nephritis can be confirmed, it will likely respond favorably to steroidal treatment and thus irreversible renal damage and chronic renal failure will be avoided.

Identifiers

PMID22475340
PMCPMC3359167
OpenAlexW2140758824

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.