ReviewCold Spring Harbor protocols2012
General principles for measuring resting membrane potential and ion concentration using fluorescent bioelectricity reporters.
Review in Cold Spring Harbor protocols, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 88 citations in OpenAlex.
- Absolute voltage mapping using dynamic photocycle control.bioRxiv : the preprint server for biology · 2026Article
- Ndt80 Orchestrates Copper Stress Responses and Mitochondrial Homeostasis inJournal of fungi (Basel, Switzerland) · 2026Article
- Article
- The Bioelectrics of Immortality and Mortality in Cold-SensitiveBioelectricity · 2025Article
- My Experiments in Bioelectricity: The Winding Road to Developmental Bioelectricity.Bioelectricity · 2025Article
- High-throughput assays to assess variant effects on disease.Disease models & mechanisms · 2024Article
- Nanotechnology and Cancer Bioelectricity: Bridging the Gap Between Biology and Translational Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Optical Estimation of Bioelectric Patterns in Living Embryos.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Information integration during bioelectric regulation of morphogenesis of the embryonic frog brain.iScience · 2023Article
- Fluorescence Imaging of Cell Membrane Potential: From Relative Changes to Absolute Values.International journal of molecular sciences · 2023Review
- Mechanobiology: A landscape for reinterpreting stem cell heterogeneity and regenerative potential in diseased tissues.iScience · 2023Review
- Article
- Cytochalasin B Modulates Nanomechanical Patterning and Fate in Human Adipose-Derived Stem Cells.Cells · 2022Article
- Ion Channel Drugs Suppress Cancer Phenotype in NG108-15 and U87 Cells: Toward Novel Electroceuticals for Glioblastoma.Cancers · 2022Article
- Cell Responsiveness to Physical Energies: Paving the Way to Decipher a Morphogenetic Code.International journal of molecular sciences · 2022Review
- Bioelectric Dysregulation in Cancer Initiation, Promotion, and Progression.Frontiers in oncology · 2022Review
- Unveiling the morphogenetic code: A new path at the intersection of physical energies and chemical signaling.World journal of stem cells · 2021Review
- Synthetic living machines: A new window on life.iScience · 2021Review
- Bioelectric signaling as a unique regulator of development and regeneration.Development (Cambridge, England) · 2021Review
- Rewiring Endogenous Bioelectric Circuits in the Xenopus laevis Embryo Model.Methods in molecular biology (Clifton, N.J.) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
This overview provides the basic information needed to understand, choose, and use fluorescent bioelectricity reporters (FBRs), where bioelectricity is defined as cell processes that involve ions or ion flux. While traditional methods of measuring these characteristics are still valid and necessary, the utility of FBRs has facilitated measurement of these properties under circumstances that are not possible with microelectrodes. Specifically, these dyes can be used to achieve subcellular resolution, to measure many cells simultaneously in vivo, and to track bioelectric gradients over long time periods despite cell movements and divisions. This article covers the basic principles underlying the interpretation of the dye signals, describes essential steps for troubleshooting, optimizing data collection, analysis, and presentation, and provides compilations of information that are useful for choosing FBRs for particular projects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.