Evidence map›Paper›PMID 22474611›Full record

ReviewCold Spring Harbor perspectives in medicine2012

The new era of the lymphatic system: no longer secondary to the blood vascular system.

Inho Choi, Sunju Lee, Young-Kwon Hong

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Glymphatics for the Neurosurgeon.Neurosurgery practice · 2023
    Review
  10. Review
  11. Role of the Renal Lymphatic System in Heart Failure.Current heart failure reports · 2023
    Review
  12. Role of miRNAs in vascular development.Non-coding RNA research · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Fluid transport in the brain.Physiological reviews · 2022
    Review
  18. Article
  19. Article
  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Inho ChoiDepartment of Surgery, Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.
Sunju Lee
Young-Kwon Hong

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The blood and lymphatic systems are the two major circulatory systems in our body. Although the blood system has been studied extensively, the lymphatic system has received much less scientific and medical attention because of its elusive morphology and mysterious pathophysiology. However, a series of landmark discoveries made in the past decade has begun to change the previous misconception of the lymphatic system to be secondary to the more essential blood vascular system. In this article, we review the current understanding of the development and pathology of the lymphatic system. We hope to convince readers that the lymphatic system is no less essential than the blood circulatory system for human health and well-being.

Indexed as

AnimalsEndothelial CellsHomeodomain ProteinsHumansLymphangiogenesisLymphangioleiomyomatosisLymphatic SystemLymphedemaProspero-Related Homeobox 1 ProteinReceptors, Vascular Endothelial Growth FactorSignal TransductionTumor Suppressor ProteinsVascular Endothelial Growth FactorsHomeodomain ProteinsProspero-Related Homeobox 1 ProteinReceptors, Vascular Endothelial Growth FactorTumor Suppressor ProteinsVascular Endothelial Growth Factors

Identifiers

PMID22474611
PMCPMC3312397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.