Evidence map›Paper›PMID 22474257›Full record

ArticleGenes & development2012

Emerging roles for specific fatty acids in developmental processes.

Tracy L Vrablik, Jennifer L Watts

Open access · diamondAbstract readComment
In one paragraph

Article in Genes & development, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Branched-Long-Chain Monomethyl Fatty Acids: Are They Hidden Gems?Journal of agricultural and food chemistry · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Regulation of body fat in Caenorhabditis elegans.Annual review of physiology · 2015
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Fat chance for longevity.Genes & development · 2013
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tracy L VrablikSchool of Molecular Biosciences, Center for Reproductive Biology, Washington State University, Pullman, Washington 99164, USA.
Jennifer L Watts
Washington State University · US

Funding

Genetic and Genomic Investigations of Fat Storage and Metabolism in C. elegansR01DK074114 · NIDDK · WASHINGTON STATE UNIVERSITY · PI WATTS, JENNIFER L · 2006 to 2013
$2.4M
NIDDK NIH HHS R01 DK074114NIDDK NIH HHS R01-DK074114
6 · The paper itself

Abstract

Animals synthesize a vast range of fatty acids serving diverse cellular functions. The roles of specific fatty acids in early development are just beginning to be characterized. In the March 15, 2012, issue of Genes & Development, Kniazeva and colleagues (pp. 554-566) describe how the particular combination of a branched chain fatty acid and an acyl-CoA synthetase is required for critical cellular processes during early embryogenesis in Caenorhabditis elegans.

Indexed as

AnimalsCaenorhabditis elegansFatty AcidsInositol 1,4,5-TrisphosphatePalmitic AcidsPhospholipidsFatty AcidsInositol 1,4,5-TrisphosphatePalmitic AcidsPhospholipids

Identifiers

PMID22474257
PMCPMC3323873
OpenAlexW2165401311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.