SynthesisCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2012
Cigarette smoking and risk of meningioma: the effect of gender.
Synthesis in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Pooled it
- Team-Based Long-Term Multidisciplinary Inpatient Neurological Rehabilitation After Surgery of Cerebral Meningioma-Outcome and Confounding Factors.Brain sciences · 2026Article
- The effect of sex on vestibular schwannoma incidence varies across the lifespan and modifies associations with race/ethnicity.Journal of neuro-oncology · 2026Article
- Hormonal factors predisposing to the development of meningiomas in men: a case-control study.Journal of neuro-oncology · 2025Article
- The effect of sex on vestibular schwannoma incidence varies across the lifespan and modifies associations with race/ethnicity.Research square · 2025Article
- Article
- Grade-stratified meningioma risk among individuals who are non-Hispanic Black and interactions with male sex.Journal of the National Cancer Institute · 2025Article
- Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients.Neuro-oncology · 2024Review
- Lifestyle and metabolic factors affect risk for meningioma in women: a prospective population-based study (The Cohort of Norway).Frontiers in oncology · 2024Article
- Integrated clinical genomic analysis reveals xenobiotic metabolic genes are downregulated in meningiomas of current smokers.Journal of neuro-oncology · 2023Article
- The joint impacts of sex and race/ethnicity on incidence of grade 1 versus grades 2-3 meningioma across the lifespan.Neuro-oncology advances · 2023Article
- Identifying brain tumor patients' subtypes based on pre-diagnostic history and clinical characteristics: a pilot hierarchical clustering and association analysis.Frontiers in oncology · 2023Article
- Peritumoral Brain Edema in Relation to Tumor Size Is a Variable That Influences the Risk of Recurrence in Intracranial Meningiomas.Tomography (Ann Arbor, Mich.) · 2022Article
- A decreased risk of meningioma in women smokers was only observed in American studies rather than studies conducted in other countries: a systematic review and meta-analysis.Chinese neurosurgical journal · 2021Article
- A meta-analysis of active smoking and risk of meningioma.Tobacco induced diseases · 2021Review
- Risk factors for childhood and adult primary brain tumors.Neuro-oncology · 2019Review
- Long-Term Use of Tamoxifen Is Associated With a Decreased Subsequent Meningioma Risk in Patients With Breast Cancer: A Nationwide Population-Based Cohort Study.Frontiers in pharmacology · 2019Article
- Birth desires and intentions of women diagnosed with a meningioma.Journal of neurosurgery · 2015Article
- Endogenous and exogenous hormone exposure and the risk of meningioma in men.Journal of neurosurgery · 2014Article
- Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females.Journal of neurosurgery · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundA number of studies have reported on the association between smoking and meningioma risk, with inconsistent findings. We examined the effect of gender on the association between cigarette smoking and risk of intracranial meningioma in a large population-based, case-control study.
methodsThe data include 1,433 intracranial meningioma cases aged 29 to 79 years diagnosed among residents of the states of Connecticut, Massachusetts, North Carolina, the San Francisco Bay Area and eight Texas counties between May 1, 2006 and April 28, 2011 as well as 1,349 controls that were frequency matched on age, sex, and geography. The data are analyzed separately and in a meta-analysis with six previously reported studies.
resultsFemale cases who reported having ever smoked were at significantly decreased risk of intracranial meningioma (OR, 0.8; 95% CI, 0.7-0.9) in contrast to male cases who were at increased risk (OR, 1.3; 95% CI, 1.0-1.7). Similar findings were noted for current and past smokers. Smoking-induced risk for females did not vary by menopausal status. For males, increased duration of use (P = 0.04) as well as increasing number of pack-years (P = 0.02) was associated with elevated risk. A meta-analysis including 2,614 cases and 1,179,686 controls resulted in an OR for ever smoking of 0.82 (95% CI, 0.68-0.98) for women and 1.39 (95% CI, 1.08-1.79) for men.
conclusionThe association of cigarette smoking and meningioma case status varies significantly by gender with women at reduced risk and men at greater risk. IMPACT: Whether the observed differences are associated with a hormonal etiology will require additional investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.