Evidence map›Paper›PMID 22473411›Full record

Trial reportClinics (Sao Paulo, Brazil)2012

Surgery with intraoperative botulinum toxin-A injection for the treatment of large-angle horizontal strabismus: a pilot study.

Nilza Minguini, Keila M M de Carvalho, Fábio L S Bosso, Fábio Endo Hirata, Newton Kara-José

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinics (Sao Paulo, Brazil), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03266549 (Botulinum Toxin Augmented Surgery Versus Conventional Surgery in the Management of Large Angle Concomitant Horizontal Deviations), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03266549 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Botulinum Toxin Augmented Surgery Versus Conventional Surgery in the Management of Large Angle Concomitant Horizontal Deviations

TypeinterventionalSponsorAssiut UniversityRan2021 to 2021Enrolled46ConditionsLarge Angle Horizontal StrabismusArmsbotulinum toxin augmented surgery, conventional surgery
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Botulinum toxin for the treatment of strabismus.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Botulinum toxin for the treatment of strabismus.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Article
  4. Use of Botulinum Toxin in Ophthalmology.Handbook of experimental pharmacology · 2021
    Article
  5. Review
  6. Medial rectus muscle elongation, a technique to treat very large-angle esotropia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2015
    Article
  7. One Year of Pediatric Ophthalmology and Strabismus Research in Review.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nilza MinguiniDepartamento de Oftalmologia, Universidade Estadual de Campinas, Campinas, SP, Brazil. minguini@uol.com.br
Keila M M de Carvalho
Fábio L S Bosso
Fábio Endo Hirata
Newton Kara-José
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultBotulinum Toxins, Type ACombined Modality TherapyEpidemiologic MethodsFemaleHumansInjectionsIntraoperative PeriodMaleNeuromuscular AgentsOphthalmologic Surgical ProceduresStrabismusTreatment OutcomeBotulinum Toxins, Type ANeuromuscular Agents

Identifiers

PMID22473411
PMCPMC3297039
OpenAlexW2152903869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.