ArticleThe Journal of comparative neurology2012
Laser-capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus.
Article in The Journal of comparative neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Brain-Wide Connectivity and Topographic Organization of Leptin Receptor Neurons in the Dorsomedial Hypothalamus.CNS neuroscience & therapeutics · 2026Article
- Leptin receptor neurons in the dorsomedial hypothalamus input to the circadian feeding network.Science advances · 2023Article
- Mapping Molecular Datasets Back to the Brain Regions They are Extracted from: Remembering the Native Countries of Hypothalamic Expatriates and Refugees.Advances in neurobiology · 2018Article
- Parvalbumin-Neurons of the Ventrolateral Hypothalamic Parvafox Nucleus Receive a Glycinergic Input: A Gene-Microarray Study.Frontiers in molecular neuroscience · 2017Article
- TRAP-seq defines markers for novel populations of hypothalamic and brainstem LepRb neurons.Molecular metabolism · 2015Article
- Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene, mimics age-associated changes in sleep quality and adiposity.Aging cell · 2015Article
- Living without insulin: the role of leptin signaling in the hypothalamus.Frontiers in neuroscience · 2015Review
- PPARγ mRNA in the adult mouse hypothalamus: distribution and regulation in response to dietary challenges.Frontiers in neuroanatomy · 2015Article
- Article
- Regionalized differentiation of CRH, TRH, and GHRH peptidergic neurons in the mouse hypothalamus.Brain structure & function · 2014Article
- Controlling feeding behavior by chemical or gene-directed targeting in the brain: what's so spatial about our methods?Frontiers in neuroscience · 2013Review
- FGF21 regulates metabolism and circadian behavior by acting on the nervous system.Nature medicine · 2013Article
- Article
- Overnight fasting regulates inhibitory tone to cholinergic neurons of the dorsomedial nucleus of the hypothalamus.PloS one · 2013Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Identifying neuronal molecular markers with restricted patterns of expression is a crucial step in dissecting the numerous pathways and functions of the brain. While the dorsomedial nucleus of the hypothalamus (DMH) has been implicated in a host of physiological processes, current functional studies have been limited by the lack of molecular markers specific for DMH. Identification of such markers would facilitate the development of mouse models with DMH-specific genetic manipulations. Here we used a combination of laser-capture microdissection (LCM) and gene expression profiling to identify genes that are highly expressed within the DMH relative to adjacent hypothalamic regions. Six of the most highly expressed of these genes, Gpr50, 4930511J11Rik, Pcsk5, Grp, Sulf1, and Rorβ, were further characterized by real-time polymerase chain reaction (PCR) analysis and in situ hybridization histochemistry. The genes identified in this article will provide the basis for future gene-targeted approaches for studying DMH function.
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