ArticleMedical care2012
The influence of health care policies and health care system distrust on willingness to undergo genetic testing.
Article in Medical care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Preferences for genetic testing among populations underrepresented in genomic research: a systematic review.European journal of human genetics : EJHG · 2025Pooled it
- Attitudes and beliefs regarding race-targeted genetic testing of Black people: A systematic review.Journal of genetic counseling · 2023Pooled it
- A Systematic Review of Discrete Choice Experiments and Conjoint Analysis on Genetic Testing.The patient · 2022Pooled it
- Awareness, knowledge, perceptions, and attitudes towards genetic testing for cancer risk among ethnic minority groups: a systematic review.BMC public health · 2017Pooled it
- Public Mistrust of the U.S. Health Care System's Profit Motives: Mixed-Methods Results from a Randomized Controlled Trial.Journal of general internal medicine · 2017Trial
- Generating Advancements in Longitudinal Analysis in X and Y Variations: Rationale, Methods, and Diagnostic Characteristics for the GALAXY Registry.American journal of medical genetics. Part A · 2026Article
- Addressing genetic discrimination for stronger legal protections and enhanced public awareness.NPJ genomic medicine · 2025Article
- Psychosocial predictors of hereditary cancer genetic testing motivation in untested individuals.Journal of genetic counseling · 2025Article
- Aging precisely: Precision medicine through the lens of an older adult.Journal of the American Geriatrics Society · 2024Review
- Understanding perceptions of tumor genomic profile testing in Black/African American cancer patients in a qualitative study: the role of medical mistrust, provider communication, and family support.Journal of community genetics · 2024Article
- Trust levels toward health care and government: insights from TrustMe, an Italian cross-sectional study.Journal of preventive medicine and hygiene · 2024Article
- Beliefs and willingness towards participating in genetic testing for depression in low-income and racial/ethnic minority mothers at-risk.Archives of psychiatric nursing · 2022Article
- Building trust in research through information and intent transparency with health information: representative cross-sectional survey of 502 US adults.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- The Genomics of Colorectal Cancer in Populations with African and European Ancestry.Cancer discovery · 2022Article
- Financial constraints on genetic counseling and further risk-management decisions among U.S. women at elevated breast cancer risk.Journal of genetic counseling · 2021Article
- Genetic Testing for Cancer Risk: Is the Community Willing to Pay for It?International journal of environmental research and public health · 2021Article
- Parental genetic knowledge and attitudes toward childhood genetic testing for inherited eye diseases.Molecular genetics & genomic medicine · 2020Article
- Article
- Increasing genomic literacy among adolescents.Genetics in medicine : official journal of the American College of Medical Genetics · 2019Article
- Psychosocial and Cultural Determinants of Interest and Uptake of Skin Cancer Genetic Testing in Diverse Primary Care.Public health genomics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
purposeAs the potential role of genetic testing in disease prevention and management grows, so does concern about differences in uptake of genetic testing across social and racial groups. Characteristics of how genetic tests are delivered may influence willingness to undergo testing and, if they affect population subgroups differently, alter disparities in testing.
methodsConjoint analysis study of the effect of 3 characteristics of genetic test delivery (ie, attributes) on willingness to undergo genetic testing for cancer risk. Data were collected using a random digit dialing survey of 128 African American and 209 white individuals living in the United States. Measures included conjoint scenarios, the Revised Health Care System Distrust Scale (including the values and competence subscales), health insurance coverage, and sociodemographic characteristics. The 3 attributes studied were disclosure of test results to the health insurer, provision of the test by a specialist or primary care doctor, and race-specific or race-neutral marketing.
resultsIn adjusted analyses, disclosure of test results to insurers, having to get the test from a specialist, and race-specific marketing were all inversely associated with willingness to undergo the genetic test, with the greatest effect for the disclosure attribute. Racial differences in willingness to undergo testing were not statistically significant (P=0.07) and the effect of the attributes on willingness to undergo testing did not vary by patient race. However, the decrease in willingness to undergo testing with insurance disclosure was greater among individuals with high values distrust (P=0.03), and the decrease in willingness to undergo testing from specialist access was smaller among individuals with high competence distrust (P=0.03).
conclusionsSeveral potentially modifiable characteristics of how genetic tests are delivered are associated with willingness to undergo testing. The effect of 2 of these characteristics vary according to the level of health care system distrust, suggesting that policy decisions about delivery of genetic testing may influence differences in uptake across patient subgroups defined by levels of distrust rather than by race.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.