ArticleIndian journal of endocrinology and metabolism2012
Interactions between thyroid disorders and kidney disease.
Article in Indian journal of endocrinology and metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 3 of them syntheses that pooled it.
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Who cites it
125 citing papers in PubMed, 3 syntheses or guidelines pooled it, 319 citations in OpenAlex.
- Prevalence and incidence of hypothyroidism and hyperthyroidism in patients with chronic kidney disease on dialysis: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- Association between hypothyroidism and risk of chronic kidney disease: evidence from a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- The correct renal function evaluation in patients with thyroid dysfunction.Journal of endocrinological investigation · 2016Pooled it
- Treatment for non-thyroidal illness syndrome in advanced chronic kidney disease: a single-blind controlled study.Journal of nephrology · 2017Trial
- Association between central thyroid hormone dysregulation and chronic kidney disease in type 2 diabetes: a cross-sectional study.Renal failure · 2026Article
- Article
- Low Dietary Iodine Intake and Sex-Specific Mortality in Kidney Transplant Recipients.Clinical journal of the American Society of Nephrology : CJASN · 2026Observational
- The abnormal thyroxine signals triggers podocyte apoptosis in DN mice.In vitro cellular & developmental biology. Animal · 2026Article
- Article
- Kidney diseases and the thyroid: interactions and consequences.Nature reviews. Endocrinology · 2026Review
- Current status of hypothyroidism control in Guangzhou area, China: a cross-sectional survey.BMC endocrine disorders · 2026Article
- Article
- Thyroid hormone replacement is associated with improvement in renal dysfunction in patients with hypothyroidism: a retrospective observational study.Frontiers in endocrinology · 2026Observational
- Clinical Pattern of Graves' Disease and Management Preferences Among Pediatric Endocrinologists in Saudi Arabia, A Decade of Experience.Clinical medicine insights. Endocrinology and diabetes · 2026Article
- Article
- Association between sensitivity to thyroid hormone indices and chronic kidney disease in US adults from NHANES 2007-2012.Renal failure · 2025Article
- Exploring the predictors of postoperative complications in hand surgery: a cross-sectional analysis.BMC surgery · 2025Article
- Saliva as a potential and non-invasive approach to identify upregulated genes associated with comorbidities of T1DM: a brief report.European journal of medical research · 2025Article
- Review
- Estimation of kidney function in Graves' disease using creatinine and cystatin C.Endocrine connections · 2025Article
65 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are several interactions between thyroid and kidney functions in each other organ's disease states. Thyroid hormones affect renal development and physiology. Thyroid hormones have pre-renal and intrinsic renal effects by which they increase the renal blood flow and the glomerular filtration rate (GFR). Hypothyroidism is associated with reduced GFR and hyperthyroidism results in increased GFR as well as increased renin - angiotensin - aldosterone activation. Chronic kidney disease (CKD) is characterized by a low T3 syndrome which is now considered a part of an atypical nonthyroidal illness. CKD patients also have increased incidence of primary hypothyroidism and subclinical hypothyroidism. The physiological benefits of a hypothyroid state in CKD, and the risk of CKD progression with hyperthyroidism emphasize on a conservative approach in the treatment of thyroid hormone abnormalities in CKD. Thyroid dysfunction is also associated with glomerulonephritis often by a common autoimmune etiology. Several drugs could affect both thyroid and kidney functions. There are few described interactions between thyroid and renal malignancies. A detailed knowledge of all these interactions is important for both the nephrologists and endocrinologists for optimal management of the patient.
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Registered trials
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