ArticlePloS one2012
Antiretroviral outcomes in South African prisoners: a retrospective cohort analysis.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- A systematic review and meta-analyses on initiation, adherence and outcomes of antiretroviral therapy in incarcerated people.PloS one · 2020Pooled it
- Pooled it
- Prisoners co-infected with tuberculosis and HIV: a systematic review.Journal of the International AIDS Society · 2016Pooled it
- Pooled it
- Trial
- Alcohol Use and HIV Suppression After Release From Prison Among People With HIV in Zambia.JAMA network open · 2025Article
- Prevalence and associated factors of TB and HIV coinfections among adult inmates with presumptive pulmonary TB in a Kenyan prison.Tropical medicine and health · 2024Article
- Imprisonment for South Ethiopian people living with HIV presents a double health burden: lived experiences of prisoners.BMC health services research · 2024Article
- Experiences of Justice-Involved People Transitioning to HIV Care in the Community After Prison Release in Lusaka, Zambia: A Qualitative Study.Global health, science and practice · 2023Article
- Factors affecting optimal adherence to antiretroviral therapy and viral suppression amongst HIV-infected prisoners in South Ethiopia: a comparative cross-sectional study.AIDS research and therapy · 2022Article
- Preferences for transitional HIV care among people living with HIV recently released from prison in Zambia: a discrete choice experiment.Journal of the International AIDS Society · 2021Article
- Intersectional Stigma Among People Transitioning From Incarceration to Community-Based HIV Care in Gauteng Province, South Africa.AIDS education and prevention : official publication of the International Society for AIDS Education · 2021Article
- Returning to care after incarceration with HIV: the French Guianese experience.BMC public health · 2020Article
- Observational study of continuity of HIV care following release from correctional facilities in South Africa.BMC public health · 2020Observational
- Loss to follow-up from antiretroviral therapy clinics: A systematic review and meta-analysis of published studies in South Africa from 2011 to 2015.Southern African journal of HIV medicine · 2019Article
- High levels of viral suppression among East African HIV-infected women and men in serodiscordant partnerships initiating antiretroviral therapy with high CD4 counts and during pregnancy.AIDS research and human retroviruses · 2018Article
- Virological outcomes of antiretroviral therapy in Zomba central prison, Malawi; a cross-sectional study.Journal of the International AIDS Society · 2017Article
- HIV and tuberculosis in prisons in sub-Saharan Africa.Lancet (London, England) · 2016Review
- Incarceration of people living with HIV/AIDS: implications for treatment-as-prevention.Current HIV/AIDS reports · 2014Article
- Incarceration is associated with used syringe lending among active injection drug users with detectable plasma HIV-1 RNA: a longitudinal analysis.BMC infectious diseases · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
methodsLittle is known about antiretroviral therapy (ART) outcomes in prisoners in Africa. We conducted a retrospective review of outcomes of a large cohort of prisoners referred to a public sector, urban HIV clinic. The review included baseline characteristics, sequential CD4 cell counts and viral load results, complications and co-morbidities, mortality and loss to follow-up up to 96 weeks on ART.
findings148 inmates (133 male) initiated on ART were included in the study. By week 96 on ART, 73% of all inmates enrolled in the study and 92% of those still accessing care had an undetectable viral load (<400 copies/ml). The median CD4 cell count increased from 122 cells/mm(3) at baseline to 356 cells/mm(3) by 96 weeks. By study end, 96 (65%) inmates had ever received tuberculosis (TB) therapy with 63 (43%) receiving therapy during the study: 28% had a history of TB prior to ART initiation, 33% were on TB therapy at ART initiation and 22% developed TB whilst on ART. Nine (6%) inmates died, 7 in the second year on ART. Loss to follow-up (LTF) was common: 14 (9%) patients were LTF whilst still incarcerated, 11 (7%) were LTF post-release and 9 (6%) whose movements could not be traced. 16 (11%) inmates had inter-correctional facility transfers and 34 (23%) were released of whom only 23 (68%) returned to the ART clinic for ongoing follow-up.
conclusionsInmates responded well to ART, despite a high frequency of TB/HIV co-infection. Attention should be directed towards ensuring eligible prisoners access ART programs promptly and that inter-facility transfers and release procedures facilitate continuity of care. Institutional TB control measures should remain a priority.
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Registered trials
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