ReviewInternational journal of environmental research and public health2012
Cumulative risk assessment: an overview of methodological approaches for evaluating combined health effects from exposure to multiple environmental stressors.
Review in International journal of environmental research and public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Atrazine and pregnancy outcomes: a systematic review of epidemiologic evidence.Birth defects research. Part B, Developmental and reproductive toxicology · 2014Pooled it
- A Detoxification Intervention for Gulf War Illness: A Pilot Randomized Controlled Trial.International journal of environmental research and public health · 2019Trial
- Toxicity and Appeal of Flavoured E-Cigarettes and Flavour Ban Outcomes: A Narrative Review.International journal of environmental research and public health · 2026Review
- Essence of toxicology research to Saudi Arabia Vision 2030 and beyond: Current state and future perspectives.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026Article
- MicroRNA-mediated changes contributing to benzo[a]pyrene toxicity in a 3D respiratory model for asthma.Current research in toxicology · 2026Article
- Cumulative risk communication: comparing practitioner perspectives with public interpretation and response.BMC public health · 2025Article
- Childhood Victimizing ACEs, Peer Victimization, Cyber Victimization: Gender Differences and Associations with Young Adult Psychological Distress.Journal of child & adolescent trauma · 2025Article
- Assessing susceptibility for polycyclic aromatic hydrocarbon toxicity in anFrontiers in toxicology · 2024Article
- Managing the effects of multiple stressors on wildlife populations in their ecosystems: developing a cumulative risk approach.Proceedings. Biological sciences · 2022Article
- Rethinking of Environmental Health Risks: A Systematic Approach of Physical-Social Health Vulnerability Assessment on Heavy-Metal Exposure through Soil and Vegetables.International journal of environmental research and public health · 2021Article
- Risk assessment of chemical mixtures by benchmark dose-principle component analysis approach in occupational exposure.Environmental science and pollution research international · 2021Article
- Mixture toxicity, cumulative risk, and environmental justice in United States federal policy, 1980-2016 : Why, with much known, was little done?Environmental health : a global access science source · 2021Article
- Characteristics and health effects of potentially pathogenic bacterial aerosols from a municipal solid waste landfill site in Hamadan, Iran.Journal of environmental health science & engineering · 2021Article
- Framing Environmental Health Decision-Making: The Struggle over Cumulative Impacts Policy.International journal of environmental research and public health · 2021Article
- Evolving Science and Practice of Risk Assessment.Risk analysis : an official publication of the Society for Risk Analysis · 2021Article
- Perceived Healthcare Access among Persons with and without HIV Who Use Illicit Stimulants: The Role of Cumulative Risk.Substance use & misuse · 2021Article
- The joint effect of ambient air pollution and agricultural pesticide exposures on lung function among children with asthma.Environmental research · 2020Article
- Rural-urban differences in estimated life expectancy associated with neighborhood-level cumulative social and environmental determinants.Preventive medicine · 2020Article
- A Cumulative Risk Perspective for Occupational Health and Safety (OHS) Professionals.International journal of environmental research and public health · 2020Article
- Impact of Filter on the Estimation of Quantitative Mixture Risk Caused by Some Chemical Constituents Generated from Popular Cigarette Brands in Iran.Addiction & health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systematic evaluation of cumulative health risks from the combined effects of multiple environmental stressors is becoming a vital component of risk-based decisions aimed at protecting human populations and communities. This article briefly examines the historical development of cumulative risk assessment as an analytical tool, and discusses current approaches for evaluating cumulative health effects from exposure to both chemical mixtures and combinations of chemical and nonchemical stressors. A comparison of stressor-based and effects-based assessment methods is presented, and the potential value of focusing on viable risk management options to limit the scope of cumulative evaluations is discussed. The ultimate goal of cumulative risk assessment is to provide answers to decision-relevant questions based on organized scientific analysis; even if the answers, at least for the time being, are inexact and uncertain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.