ArticleInternational journal of environmental research and public health2012
Relative pesticide and exposure route contribution to aggregate and cumulative dose in young farmworker children.
Article in International journal of environmental research and public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 42 citations in OpenAlex.
- Methodologies for the collection of parameters to estimate dust/soil ingestion for young children.Frontiers in public health · 2024Article
- Measured and Modeled Comparisons of Chemical and Microbial Contaminants in Tap and Bottled Water in a US-Mexico Border Community.ACS ES&T water · 2022Article
- Exploring spatial averaging of contamination in fomite microbial transfer models and implications for dose.Journal of exposure science & environmental epidemiology · 2022Article
- RETRACTED: Health risk assessment of exposure to chlorpyrifos in pregnant women using deterministic and probabilistic approaches.PloS one · 2022Article
- Urinary organophosphate metabolites and oxidative stress in children living in agricultural and urban communities.Environmental science and pollution research international · 2020Article
- Soil, Hand, and Body Adherence Measures across Four Beach Areas: Potential Influence on Exposure to Oil Spill Chemicals.International journal of environmental research and public health · 2020Article
- Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program.Journal of exposure science & environmental epidemiology · 2020Review
- Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research.Environmental health perspectives · 2019Article
- Maternal residential pesticide use and risk of childhood leukemia in Costa Rica.International journal of cancer · 2018Article
- Pesticides Are an Occupational and Public Health Issue.International journal of environmental research and public health · 2018Article
- Mouthing activity data for children age 3 to <6 years old and fraction of hand area mouthed for children age <6 years old in Taiwan.Journal of exposure science & environmental epidemiology · 2018Article
- Longitudinal assessment of occupational determinants of chlorpyrifos exposure in adolescent pesticide workers in Egypt.International journal of hygiene and environmental health · 2017Article
- Temporal Trends of Insecticide Concentrations in Carpet Dust in California from 2001 to 2006.Environmental science & technology · 2016Article
- Hand- and Object-Mouthing of Rural Bangladeshi Children 3-18 Months Old.International journal of environmental research and public health · 2016Article
- Modeling of human viruses on hands and risk of infection in an office workplace using micro-activity data.Journal of occupational and environmental hygiene · 2015Article
- Cumulative risk assessment: an overview of methodological approaches for evaluating combined health effects from exposure to multiple environmental stressors.International journal of environmental research and public health · 2012Review
- Mouthing activity data for children aged 7 to 35 months in Taiwan.Journal of exposure science & environmental epidemiologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
The Child-Specific Aggregate Cumulative Human Exposure and Dose (CACHED) framework integrates micro-level activity time series with mechanistic exposure equations, environmental concentration distributions, and physiologically-based pharmacokinetic components to estimate exposure for multiple routes and chemicals. CACHED was utilized to quantify cumulative and aggregate exposure and dose estimates for a population of young farmworker children and to evaluate the model for chlorpyrifos and diazinon. Micro-activities of farmworker children collected concurrently with residential measurements of pesticides were used in the CACHED framework to simulate 115,000 exposure scenarios and quantify cumulative and aggregate exposure and dose estimates. Modeled metabolite urine concentrations were not statistically different than concentrations measured in the urine of children, indicating that CACHED can provide realistic biomarker estimates. Analysis of the relative contribution of exposure route and pesticide indicates that in general, chlorpyrifos non-dietary ingestion exposure accounts for the largest dose, confirming the importance of the micro-activity approach. The risk metrics computed from the 115,000 simulations, indicate that greater than 95% of these scenarios might pose a risk to children's health from aggregate chlorpyrifos exposure. The variability observed in the route and pesticide contributions to urine biomarker levels demonstrate the importance of accounting for aggregate and cumulative exposure in establishing pesticide residue tolerances in food.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.