ArticleAnnals of surgery2012
Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures.
Article in Annals of surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00257231 (Inflammation and the Host Response to Injury), which is not on this map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Inflammation and the Host Response to Injury
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guidelines for Essential Trauma Care: Second Edition (2026).World journal of surgery · 2026Guideline
- Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the Intensive Care Unit: A Stepped-Wedge Cluster Randomized Clinical Trial.JAMA surgery · 2018Trial
- Genomic responses in mouse models poorly mimic human inflammatory diseases.Proceedings of the National Academy of Sciences of the United States of America · 2013Trial
- Designing and Implementing a Simulation-Based Pediatric Trauma Training Program in a Resource-Limited Setting: The PRACTICE Study.Pediatric reports · 2026Article
- Attenuated interferon-γ following injury is associated with chronic critical illness.The journal of trauma and acute care surgery · 2025Article
- Intra-hospital MRI transport in neurocritical patients with aneurysmal subarachnoid hemorrhage: complications and clinical impact with predominant continuation of care.Neurosurgical review · 2025Article
- THE EFFECT OF IN-BED LEG CYCLING EXERCISES ON MUSCLE STRENGTH IN PATIENTS WITH INTENSIVE CARE UNIT-ACQUIRED WEAKNESS: A SINGLE-CENTER RETROSPECTIVE STUDY.Journal of rehabilitation medicine. Clinical communications · 2023Article
- Multi-Omic Admission-Based Prognostic Biomarkers Identified by Machine Learning Algorithms Predict Patient Recovery and 30-Day Survival in Trauma Patients.Metabolites · 2022Article
- Recent Developments in Mouse Trauma Research Models: A Mini-Review.Frontiers in physiology · 2022Review
- Chronic critical illness after hypothermia in trauma patients.Trauma surgery & acute care open · 2021Article
- Interdisciplinary clinical debriefing in the emergency department: an observational study of learning topics and outcomes.BMC emergency medicine · 2020Observational
- Safety of Early MRI Examinations in Severe TBI: A Test Battery for Proper Patient Selection.Frontiers in neurology · 2020Article
- Cell-free nuclear, but not mitochondrial, DNA concentrations correlate with the early host inflammatory response after severe trauma.Scientific reports · 2019Article
- Association between age and acute respiratory distress syndrome development and mortality following trauma.The journal of trauma and acute care surgery · 2019Article
- Using theories of behaviour change to transition multidisciplinary trauma team training from the training environment to clinical practice.Implementation science : IS · 2019Article
- Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery.Surgery · 2018Review
- Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients.The journal of trauma and acute care surgery · 2018Observational
- Mouse Injury Model of Polytrauma and Shock.Methods in molecular biology (Clifton, N.J.) · 2018Review
- A Novel Approach to Identify Polytraumatized Patients in Extremis.BioMed research international · 2018Article
- The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers.Critical care medicine · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
Abstract
objectiveTo determine and compare outcomes with accepted benchmarks in trauma care at 7 academic level I trauma centers in which patients were treated on the basis of a series of standard operating procedures (SOPs).
backgroundInjury remains the leading cause of death for those younger than 45 years. This study describes the baseline patient characteristics and well-defined outcomes of persons hospitalized in the United States for severe blunt trauma.
methodsWe followed 1637 trauma patients from 2003 to 2009 up to 28 hospital days using SOPs developed at the onset of the study. An extensive database on patient and injury characteristics, clinical treatment, and outcomes was created. These data were compared with existing trauma benchmarks.
resultsThe study patients were critically injured and were in shock. SOP compliance improved 10% to 40% during the study period. Multiple organ failure and mortality rates were 34.8% and 16.7%, respectively. Time to recovery, defined as the time until the patient was free of organ failure for at least 2 consecutive days, was developed as a new outcome measure. There was a reduction in mortality rate in the cohort during the study that cannot be explained by changes in the patient population.
conclusionsThis study provides the current benchmark and the overall positive effect of implementing SOPs for severely injured patients. Over the course of the study, there were improvements in morbidity and mortality rates and increasing compliance with SOPs. Mortality was surprisingly low, given the degree of injury, and improved over the duration of the study, which correlated with improved SOP compliance.
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Registered trials
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