Evidence map›Paper›PMID 22469631›Full record

ArticleEmerging infectious diseases2012

Shiga toxin-producing Escherichia coli serotype O78:H(-) in family, Finland, 2009.

Taru Lienemann, Eeva Salo, Ruska Rimhanen-Finne, Kai Rönnholm, Mari Taimisto, Jari J Hirvonen, Eveliina Tarkka, Markku Kuusi, Anja Siitonen

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Emerging infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Estimating the burden of foodborne diseases in Japan.Bulletin of the World Health Organization · 2015
    Pooled it
  2. Shiga Toxin-ProducingMicroorganisms · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Outbreak of multiple strains of non-O157 Shiga toxin-producing and enteropathogenicEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
    Article
  10. Article
  11. Genetic Analysis of Virulence Potential ofFrontiers in microbiology · 2018
    Article
  12. Article
  13. Shiga Toxin Subtypes of Non-O157Frontiers in cellular and infection microbiology · 2017
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Taru LienemannNational Institute for Health and Welfare, Helsinki, Finland.
Eeva Salo
Ruska Rimhanen-Finne
Kai Rönnholm
Mari Taimisto
Jari J Hirvonen
Eveliina Tarkka
Markku Kuusi
Anja Siitonen
Finnish Institute for Health and Welfare · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shiga toxin-producing Escherichia coli (STEC) is a pathogen that causes gastroenteritis and bloody diarrhea but can lead to severe disease, such as hemolytic uremic syndrome (HUS). STEC serotype O78:H(-) is rare among humans, and infections are often asymptomatic. We detected a sorbitol-fermenting STEC O78:H(-):stx(1c):hlyA in blood and fecal samples of a 2-week-old boy who had bacteremia and HUS and in fecal samples of his asymptomatic family members. The phenotypic and genotypic characteristics and the virulence properties of this invasive STEC were investigated. Our findings demonstrate that contrary to earlier suggestions, STEC under certain conditions can invade the human bloodstream. Moreover, this study highlights the need to implement appropriate diagnostic methods for identifying the whole spectrum of STEC strains associated with HUS.

Indexed as

Anti-Bacterial AgentsBacteremiaCluster AnalysisDiarrhea, InfantileEscherichia coli InfectionsFecesHumansInfant, NewbornMaleMolecular TypingPhenotypeSequence Analysis, DNAShiga-Toxigenic Escherichia coliShiga Toxin 1Virulence FactorsAnti-Bacterial AgentsShiga Toxin 1Virulence Factors

Identifiers

PMID22469631
PMCPMC3309701
OpenAlexW2128076427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.