Evidence map›Paper›PMID 22469254›Full record

ReviewChild development

Child development and molecular genetics: 14 years later.

Robert Plomin

Abstract readReview
In one paragraph

Review in Child development. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  18. Does IQ Really Predict Job Performance?Applied developmental science · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Robert PlominKing's College London. robert.plomin@kcl.ac.uk

Funding

Genetics, School environments and cognitive developmentR01HD044454 · NICHD · KING'S COLLEGE LONDON · PI PLOMIN, ROBERT · 2005 to 2014
$3.4M
GENETICS OF GENERAL AND SPECIFIC MATH DISABILITIESR01HD046167 · NICHD · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI PETRILL, STEPHEN A · 2003 to 2005
$1.6M
Medical Research Council G0500079Medical Research Council G0500079(73692)Medical Research Council G19/2NICHD NIH HHS HD44454NICHD NIH HHS HD46167NICHD NIH HHS R01 HD044454NICHD NIH HHS R01 HD046167
6 · The paper itself

Abstract

Fourteen years ago, the first article on molecular genetics was published in this journal: Child Development, Molecular Genetics, and What to Do With Genes Once They Are Found (R. Plomin & M. Rutter, 1998). The goal of the article was to outline what developmentalists can do with genes once they are found. These new directions for developmental research are still relevant today. The problem lies with the phrase "once they are found": It has been much more difficult than expected to identify genes responsible for the heritability of complex traits and common disorders, the so-called missing heritability problem. The present article considers reasons for the missing heritability problem and possible solutions.

Indexed as

ChildChild DevelopmentDevelopmental DisabilitiesEpigenesis, GeneticEpistasis, GeneticFollow-Up StudiesGenesGenetic Predisposition to DiseaseGenome, HumanGenome-Wide Association StudyGenomic Structural VariationHumansOligonucleotide Array Sequence Analysis

Identifiers

PMID22469254
PMCPMC3593231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.