Evidence map›Paper›PMID 22469110›Full record

ReviewNutrition (Burbank, Los Angeles County, Calif.)2012

What is dynapenia?

Brian C Clark, Todd M Manini

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrition (Burbank, Los Angeles County, Calif.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 198 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
198citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06621875 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Effect Of The Presence Of Dynapenia On Posture, Spine Muscle Elasticity, Strength And Endurance In Young Adults

TypeobservationalSponsorAynur AyazzadeRan2024 to 2025Enrolled40ConditionsDynapenia, Muscle Weakness, Sarcopenia
NCT07253714 nacompletednot on this mapstarted 2024, after this paper: background citation

The effect of proprioceptive exercise training on cervical proprioception, kinesiophobia, and pain catastrophizing levels in sarcopenic geriatric individuals residing in nursing homes

TypeinterventionalSponsorAtılım UniversityRan2024 to 2024Enrolled31ConditionsSarcopenia in ElderlyArmsClassic exercises, Proprioceptive exercise training
3 · Its place in the literature

Who cites it

198 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  4. Correlation between Handgrip Strength and Depression in Older Adults-A Systematic Review and a Meta-Analysis.International journal of environmental research and public health · 2021
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  5. Influence of Resistance Training on Gait & Balance Parameters in Older Adults: A Systematic Review.International journal of environmental research and public health · 2021
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138 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brian C ClarkOhio Musculoskeletal and Neurological Institute (OMNI) and Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA. clarkb2@ohio.edu
Todd M Manini

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
Intracortical Mechanisms of Muscle WeaknessR15HD065552 · NICHD · OHIO UNIVERSITY ATHENS · PI CLARK, BRIAN C · 2010 to 2011
$620k
Task Specific Exercise for the Clinically DisabledR21AG031974 · NIA · UNIVERSITY OF FLORIDA · PI MANINI, TODD · 2009 to 2010
$328k
NIA NIH HHS P30 AG028740NIA NIH HHS P30AG028740NIA NIH HHS R21 AG031974NIA NIH HHS R21AG031974NICHD NIH HHS R15 HD065552NICHD NIH HHS R15HD065552
6 · The paper itself

Abstract

Dynapenia (pronounced dahy-nuh-pē-nē-a, Greek translation for poverty of strength, power, or force) is the age-associated loss of muscle strength that is not caused by neurologic or muscular diseases. Dynapenia predisposes older adults to an increased risk for functional limitations and mortality. For the past several decades, the literature has largely focused on muscle size as the primary cause of dynapenia; however, recent findings have clearly demonstrated that muscle size plays a relatively minor role. Conversely, subclinical deficits in the structure and function of the nervous system and/or impairments in the intrinsic force-generating properties of skeletal muscle are potential antecedents to dynapenia. This review highlights in the contributors to dynapenia and the etiology and risk factors that predispose individuals to dynapenia. In addition, we address the role of nutrition in the muscular and neurologic systems for the preservation of muscle strength throughout the life span.

Indexed as

Nutritional Physiological PhenomenaAdultAgingHumansMuscle, SkeletalMuscle StrengthMuscle WeaknessRisk FactorsSarcopenia

Identifiers

PMID22469110
PMCPMC3571692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.