ArticleJournal of Korean medical science2012
Neurologic complications and outcomes of pandemic (H1N1) 2009 in Korean children.
Article in Journal of Korean medical science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review.Case reports in neurological medicine · 2025Article
- The role of fever in febrile seizures: major implications for fever perception.Frontiers in pediatrics · 2023Article
- Clinical Spectrum and Burden of Influenza-Associated Neurological Complications in Hospitalised Paediatric Patients.Frontiers in pediatrics · 2021Article
- Neurological associations of COVID-19.The Lancet. Neurology · 2020Review
- Letter: Neurological Implications of COVID-19 and Lessons Learned From Prior Epidemics and Pandemics.Neurosurgery · 2020Article
- Characteristics and Outcomes of Influenza-Associated Encephalopathy Cases Among Children and Adults in Japan, 2010-2015.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Neuroinfluenza: evaluation of seasonal influenza associated severe neurological complications in children (a multicenter study).Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- Successful Treatment of Influenza-Associated Acute Necrotizing Encephalitis in an Adult Using High-Dose Oseltamivir and Methylprednisolone: Case Report and Literature Review.Open forum infectious diseases · 2017Review
- Neurological events related to influenza A (H1N1) pdm09.Influenza and other respiratory viruses · 2014Review
- Recurrent plastic bronchitis in a child with 2009 influenza A (H1N1) and influenza B virus infection.Journal of Korean medical science · 2012Article
- A Favorable Treatment Outcome inChild neurology openArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurologic complications of children with influenza A H1N1 2009 pandemic, diagnosed in two consecutive influenza seasons were retrospectively reviewed to seek better outcomes in future outbreaks. Patient demographics, clinical manifestations and neurologic outcomes were reviewed. A total of 1,389 children were diagnosed with influenza A H1N1 by real-time reverse transcriptase-polymerase chain reaction. Of these, 23 (1.7%) patients had neurologic involvement. Their mean age was 5.9 ± 3.6 yr (range, 6 months to 11 yr) and 16 (69.9%) were boys. None of the 23 patients had been vaccinated for influenza A H1N1 and seasonal influenzas. Twenty-two of the 23 patients presented with seizures. Clinical features included febrile convulsion (n = 19), afebrile convulsion (n = 1), aseptic meningitis (n = 1), encephalopathy (n = 1), and acute necrotizing encephalopathy (n = 1). They all were treated with Oseltamivir twice daily for 5 days immediately after nasal and throat swab testing. Twenty-one of the subjects recovered fully, but the youngest two infants experienced severe neurological sequelae. The results indicate that neurologic complications associated with influenza A H1N1 2009 pandemic were mostly mild, but rarely were serious. Prompt intervention leads to a better outcome and vaccination may prevent the disease, thus staving off serious neurological complications following influenza, especially in young infants.
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