Evidence map›Paper›PMID 22467985›Full record

Trial reportSleep2012

The impact of a telemedicine monitoring system on positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trial.

Nurit Fox, A J Hirsch-Allen, Elizabeth Goodfellow, Joshua Wenner, John Fleetham, C Frank Ryan, Mila Kwiatkowska, Najib T Ayas

5 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Sleep, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 78 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 8 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02279901 nacompletednot on this mapstarted 2014, after this paper: background citation

Impact of Interactive Web-Based Education and Interactive Voice Response (Automated Follow-up) Programs on CPAP Adherence for the Treatment of Obstructive Sleep Apnea

TypeinterventionalSponsorKaiser PermanenteRan2014 to 2016Enrolled1,873ConditionsObstructive Sleep ApneaArmsTelemedicine Education, IVR
NCT03243487 nacompletednot on this mapstarted 2017, after this paper: background citation

ThErapy Adherence Management in Veterans: A Randomized Trial

TypeinterventionalSponsorUniversity of FloridaRan2017 to 2019Enrolled250ConditionsObstructive Sleep Apnea of AdultArmsstructured adherence management program, Standard of care
NCT04559737 nawithdrawnnot on this mapstarted 2020, after this paper: background citation

Impact of Population Management Strategies on Continuous Positive Airway Pressure Adherence

TypeinterventionalSponsorKaiser PermanenteRan2020 to 2020Enrolled0ConditionsObstructive Sleep Apnea (OSA)ArmsCase Management
NCT04752462 nacompletednot on this mapstarted 2021, after this paper: background citation

Effect of Post-Discharge Telemedicine Motivational Enhancement Intervention in Heart Failure and Obstructive Sleep Apnea on Adherence and Health Outcomes

TypeinterventionalSponsorThe Cleveland ClinicRan2021 to 2025Enrolled75ConditionsAcute Decompensated Heart Failure, Obstructive Sleep Apnea, Motivational Enhancement, PAP AdherenceArmsTelemedicine Intensive Motivational Enhancement
NCT07377968 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy of Wearable Device to Promote CPAP Adherence in Patients With Obstructive Sleep Apnea (OSA); A Randomized Controlled Trial

TypeinterventionalSponsorRamathibodi HospitalRan2026 to 2026Enrolled80ConditionsObstructive Sleep Apnea (OSA)Armsgarmin vivoactive 5 with self-monitoring data, Garmin vivoactive 5 without self-monitoring data
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 8 syntheses or guidelines pooled it, 196 citations in OpenAlex.

  1. Pooled it
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  4. The Effect of Patient-Facing Applications on Positive Airway Pressure Therapy Adherence: A Systematic Review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Pooled it
  5. Treatment of Adult Obstructive Sleep Apnea With Positive Airway Pressure: An American Academy of Sleep Medicine Systematic Review, Meta-Analysis, and GRADE Assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Pooled it
  6. Remote Patient Monitoring via Non-Invasive Digital Technologies: A Systematic Review.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2017
    Pooled it
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  15. Efficacy of a telemonitoring system in continuous positive airway pressure therapy in Asian obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
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  17. Effect of cloud-based sleep coaches on positive airway pressure adherence.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nurit FoxSleep Disorders Program, University of British Columbia Hospital, Vancouver, British Columbia, Canada.
A J Hirsch-Allen
Elizabeth Goodfellow
Joshua Wenner
John Fleetham
C Frank Ryan
Mila Kwiatkowska
Najib T Ayas
University of British Columbia Hospital · CAProvidence Health Care · CAThompson Rivers University · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesFirst-line therapy for patients with moderate to severe obstructive sleep apnea (OSA) is positive airway pressure (PAP). Although PAP is a highly efficacious treatment, adherence to PAP is still a substantial clinical problem. The objective of this study was to determine whether PAP adherence can be improved with a telemedicine monitoring system.

designA nonblinded, single-center, randomized controlled trial that compared standard PAP treatment versus PAP treatment and a telemedicine monitoring system

settingUniversity sleep disorders program in British Columbia, Canada PATIENTS: Adult patients (≥ 19 yr of age) with moderate to severe OSA (apnea hypopnea index (AHI) ≥ 15 events/hr determined by polysomnography) prescribed PAP

interventionsPatients were randomized to either standard care with an autotitrating PAP machine or an autotitrating PAP machine that transmitted physiologic information (i.e., adherence, air leak, residual AHI) daily to a website that could be reviewed. If problems were identified from information from the website, the patient was contacted by telephone as necessary. MEASUREMENTS: PAP adherence after 3 mo, subjective sleep quality, and side effects

resultsSeventy-five patients were enrolled; 39 were randomized to telemedicine and 36 to standard care. The mean age ± standard deviation (SD) was 53.5 ± 11.2 yr, mean AHI was 41.6 ± 22.1 events/hr, and 80% of patients were male. After 3 mo, mean PAP adherence was significantly greater in the telemedicine arm (191 min per day) versus the standard arm (105 min per day; mean difference = 87 min, 95% confidence interval (CI): 25-148 min, P = 0.006, unpaired t test). On days when PAP was used, mean adherence was 321 min in the telemedicine arm and 207 min in the standard arm (difference = 113 min, 95% CI: 62-164 min, P < 0.0001). Significant independent predictors of adherence included age, baseline Epworth Sleepiness Scale score, and use of telemedicine. On average, an additional 67 min of technician time was spent on patients in the telemedicine arm compared with the standard arm (P = 0.0001).

conclusionsPAP adherence can be improved with the use of a web-based telemedicine system at the initiation of treatment.

Indexed as

Continuous Positive Airway PressurePatient CompliancePolysomnographyTelemedicineAdultBody Mass IndexCohort StudiesFemaleHumansMaleMiddle AgedSleep Apnea, ObstructiveTime FactorsTreatment OutcomeadherenceObstructive sleep apneapositive airway pressureremote monitoringtelemedicine

Identifiers

PMID22467985
PMCPMC3296789
OpenAlexW2080125767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.