Evidence map›Paper›PMID 22467848›Full record

ArticleJournal of geriatric psychiatry and neurology2012

Characteristics associated with inpatient versus outpatient status in older adults with bipolar disorder.

Rayan K Al Jurdi, Herbert C Schulberg, Rebecca L Greenberg, Mark E Kunik, Ariel Gildengers, Martha Sajatovic, Benoit H Mulsant, Robert C Young, GERI-BD Study Group

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of geriatric psychiatry and neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00254488 (Acute Pharmacotherapy of Late-Life Mania), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00254488 phase4completednot on this map

Acute Pharmacotherapy of Late-Life Mania (GERI-BD)

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2005 to 2011Enrolled224ConditionsBipolar Disorder, ManiaArmsLithium (LI), Divalproex (DV)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Assessing bipolar disorder in the older adult: the GERI-BD toolbox.International journal of geriatric psychiatry · 2018
    Trial
  2. Article
  3. Article
  4. Review
  5. Late-life psychosis: diagnosis and treatment.Current psychiatry reports · 2015
    Review
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Rayan K Al JurdiThe Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA. rayana@bcm.tmc.edu
Herbert C Schulberg
Rebecca L Greenberg
Mark E Kunik
Ariel Gildengers
Martha Sajatovic
Benoit H Mulsant
Robert C Young
GERI-BD Study Group
Cornell University · USCase Western Reserve University · USCentre for Addiction and Mental Health · CAMental Illness Research, Education and Clinical Centers · USMichael E. DeBakey VA Medical Center · USUniversity of Pittsburgh · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024996 · NCRR · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2007 to 2011
$49.6M
Research Methods CoreP30MH085943 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2009 to 2013
$9.2M
Acute Pharmacotherapy of Late-Life Mania-Study Coordinating CenterU01MH074511 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI YOUNG, ROBERT C. · 2005 to 2009
$1.3M
Treatment of Bipolar Disorder in Old AgeK02MH067028 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI YOUNG, ROBERT C. · 2003 to 2013
$1.2M
Acute Pharmacotherapy of Late-Life ManiaU01MH068847 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI YOUNG, ROBERT C. · 2005 to 2009
$650k
NCRR NIH HHS UL1 RR024989NCRR NIH HHS UL1 RR024996NIMH NIH HHS K02 MH067028NIMH NIH HHS P30 MH085943NIMH NIH HHS U01 MH068847NIMH NIH HHS U01-MH068847NIMH NIH HHS U01 MH074511NIMH NIH HHS U01-MH074511
6 · The paper itself

Abstract

objectivesThis is an exploratory analysis of ambulatory and inpatient services utilization by older persons with type I bipolar disorder experiencing elevated mood. The association between type of treatment setting and the person's characteristics is explored within a framework that focuses upon predisposing, enhancing, and need characteristics.

methodBaseline assessments were conducted with the first 51 inpatients and 49 outpatients 60 years of age and older, meeting criteria for type I bipolar disorder, manic, hypomanic, or mixed episode enrolled in the geriatric bipolar disorder study (GERI-BD) study. We compared participants recruited from inpatient versus outpatient settings in regard to the patients' predisposing, enabling, and need characteristics.

resultsBeing treated in an inpatient rather than an outpatient setting was associated with the predisposing characteristic of being non-Hispanic caucasian (odds ratio [OR]: 0.1; P = .005) and past history of treatment with first-generation antipsychotics (OR: 6.5; P < .001), and the need characteristic reflected in having psychotic symptoms present in the current episode (OR: 126.08; P < .001).

conclusionEthnicity, past pharmacologic treatment, and current symptom severity are closely associated with treatment in inpatient settings. Clinicians and researchers should investigate whether closer monitoring of persons with well-validated predisposing and need characteristics can lead to their being treated in less costly but equally effective ambulatory rather than inpatient settings.

Indexed as

AgedAged, 80 and overAge FactorsAmbulatory CareBipolar DisorderFemaleHospitalizationHumansInpatientsMaleMiddle AgedNeuropsychological TestsOutpatientsPsychiatric Status Rating Scales

Identifiers

PMID22467848
PMCPMC3623950
OpenAlexW1974937307

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.