ArticleApplied and environmental microbiology2012
Contact-free inactivation of Candida albicans biofilms by cold atmospheric air plasma.
Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.
- Disinfection of dental root canals by cold atmospheric plasma: a systematic review and meta-analysis of dental biofilm.Frontiers in oral health · 2024Pooled it
- Optimizing and tailoring cold atmospheric plasma parameters forFrontiers in microbiology · 2026Article
- Understanding Heterogeneity and Tolerance of Dual Candida albicans-Staphylococcus aureus Biofilms to Cold Atmospheric Plasma and Antimicrobial Combinations.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025Article
- The effects of ex vivo physical cold atmospheric plasma treatment on endothelial cells in human corneal explants and its potential for in vivo application in refractory corneal ulcers.Scientific reports · 2025Article
- Comparing the Effect of Photodynamic Therapy With 660 and 450 nm Lasers and Cold Atmospheric Plasma onJournal of lasers in medical sciences · 2025Article
- Efficacy of Cold Atmospheric Plasma in Chronic Diabetic Foot Ulcer Management: A Case Report.The American journal of case reports · 2024Article
- Proposing an Affordable Plasma Device for Polymer Surface Modification and Microbial Inactivation.Molecules (Basel, Switzerland) · 2024Article
- Low-Temperature Plasma Techniques in Biomedical Applications and Therapeutics: An Overview.International journal of molecular sciences · 2023Review
- Strategies for Bacterial Eradication from Human and Animal Semen Samples: Current Options and Future Alternatives.Sensors (Basel, Switzerland) · 2023Review
- Orthopaedic applications of cold physical plasma.EFORT open reviews · 2023Review
- Removal of chemical and microbial water pollutants by cold plasma combined with Ag/TiOScientific reports · 2022Article
- Application of Non-Thermal Plasma to Fungal Resources.Journal of fungi (Basel, Switzerland) · 2022Review
- Behavior of the Surviving Population ofFrontiers in microbiology · 2022Article
- Treatment of Fungal-Infected Diabetic Wounds with Low Temperature Plasma.Biomedicines · 2021Article
- Inactivation of Staphylococcus aureus and Escherichia coli Biofilms by Air-Based Atmospheric-Pressure DBD Plasma.Applied biochemistry and biotechnology · 2021Article
- Effect of Cold Atmospheric Plasma Jet Associated to Polyene Antifungals onMolecules (Basel, Switzerland) · 2021Article
- The Antimicrobial Effect of Cold Atmospheric Plasma against Dental Pathogens-A Systematic Review of In-Vitro Studies.Antibiotics (Basel, Switzerland) · 2021Review
- Potential of Cold Plasma Technology in Ensuring the Safety of Foods and Agricultural Produce: A Review.Foods (Basel, Switzerland) · 2020Review
- TheFrontiers in microbiology · 2020Article
- Antimicrobial effects of microwave-induced plasma torch (MiniMIP) treatment on Candida albicans biofilms.Microbial biotechnology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Candida albicans is one of the main species able to form a biofilm on almost any surface, causing both skin and superficial mucosal infections. The worldwide increase in antifungal resistance has led to a decrease in the efficacy of standard therapies, prolonging treatment time and increasing health care costs. Therefore, the aim of this work was to demonstrate the applicability of atmospheric plasma at room temperature for inactivating C. albicans growing in biofilms without thermally damaging heat-sensitive materials. This so-called cold atmospheric plasma is produced by applying high voltage to accelerate electrons, which ionize the surrounding air, leading to the production of charged particles, reactive species, and photons. A newly developed plasma device was used, which exhibits a large plasma-generating surface area of 9 by 13 cm (117 cm(2)). Different time points were selected to achieve an optimum inactivation efficacy range of ≥3 log(10) to 5 log(10) reduction in CFU per milliliter, and the results were compared with those of 70% ethanol. The results obtained show that contact-free antifungal inactivation of Candida biofilms by cold atmospheric plasma is a promising tool for disinfection of surfaces (and items) in both health care settings and the food industry, where ethanol disinfection should be avoided.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.