ArticleGenetics2012
Investigating natural variation in Drosophila courtship song by the evolve and resequence approach.
Article in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
69 citing papers in PubMed.
- Intersecting experimental evolution and CRISPR screens to identify novel toxin resistance loci.eLife · 2026Article
- Genomics of Experimental Adaptive Radiation in the Cryptic Coloration of Feather Lice.Genome biology and evolution · 2025Article
- Article
- A Path Integral Approach for Allele Frequency Dynamics Under Polygenic Selection.bioRxiv : the preprint server for biology · 2024Article
- Genetic basis and repeatability for desiccation resistance in Drosophila melanogaster (Diptera: Drosophilidae).Genetica · 2024Article
- Artificial selection reveals complex genetic architecture of shoot branching and its response to nitrate supply in Arabidopsis.PLoS genetics · 2023Article
- Estimating Temporally Variable Selection Intensity from Ancient DNA Data.Molecular biology and evolution · 2023Article
- Adaptation in Outbred Sexual Yeast is Repeatable, Polygenic and Favors Rare Haplotypes.Molecular biology and evolution · 2022Article
- Natural alleles at theProceedings. Biological sciences · 2022Article
- Genome-wide selection signatures reveal widespread synergistic effects of two different stressors inProceedings. Biological sciences · 2022Article
- Experimental evolution reveals complex responses to environmental change.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- A genome-wide test for paternal indirect genetic effects on lifespan inProceedings. Biological sciences · 2022Article
- Article
- An Experimental Test of Adaptive Introgression in Locally Adapted Populations of Splash Pool Copepods.Molecular biology and evolution · 2021Article
- Low concordance of short-term and long-term selection responses in experimental Drosophila populations.Molecular ecology · 2020Article
- Estimating the genome-wide contribution of selection to temporal allele frequency change.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Combining Experimental Evolution and Genomics to Understand How Seed Beetles Adapt to a Marginal Host Plant.Genes · 2020Article
- Inference of natural selection from ancient DNA.Evolution letters · 2020Article
- Secondary Evolve and Resequencing: An Experimental Confirmation of Putative Selection Targets without Phenotyping.Genome biology and evolution · 2020Article
- Predicting Thermal Adaptation by Looking Into Populations' Genomic Past.Frontiers in genetics · 2020Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
A primary goal of population genetics is to determine the genetic basis of natural trait variation. We could significantly advance this goal by developing comprehensive genome-wide approaches to link genotype and phenotype in model organisms. Here we combine artificial selection with population-based resequencing to investigate the genetic basis of variation in the interpulse interval (IPI) of Drosophila melanogaster courtship song. We performed divergent selection on replicate populations for only 14 generations, but had considerable power to differentiate alleles that evolved due to selection from those that evolved stochastically. We identified a large number of variants that changed frequency in response to selection for this simple behavior, and they are highly underrepresented on the X chromosome. Though our power was adequate using this experimental technique, the ability to differentiate causal variants from those affected by linked selection requires further development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.