Evidence map›Paper›PMID 22466032›Full record

ArticleJournal of medical microbiology2012

Identification of porcine rotavirus-like genotype P[6] strains in Taiwanese children.

Kao-Pin Hwang, Fang-Tzy Wu, Krisztián Bányai, Ho-Sheng Wu, Dustin Chen-Fu Yang, Yhu-Chering Huang, Jen-Shiou Lin, Chao Agnes Hsiung, Jason C Huang, Baoming Jiang and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of medical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  7. Whole-genome sequencing and analyses identify high genetic heterogeneity, diversity and endemicity of rotavirus genotype P[6] strains circulating in Africa.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2018
    Article
  8. Review
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  11. Review of global rotavirus strain prevalence data from six years post vaccine licensure surveillance: is there evidence of strain selection from vaccine pressure?Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014
    Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Kao-Pin HwangDivision of Pediatric Infectious Disease, Department of Pediatrics, China Medical University Hospital, China Medical University School of Medicine, Taichung, Taiwan ROC.
Fang-Tzy WuDepartment of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan ROC.
Krisztián BányaiVeterinary Medical Research Institute, Budapest, Hungary.
Ho-Sheng WuSchool of Medical Laboratory Science and Biotechnology, Taipei Medical University, Taipei, Taiwan ROC.
Dustin Chen-Fu YangCenters for Disease Control, Department of Health, Taiwan ROC.
Yhu-Chering HuangDivision of Pediatric Infectious Disease, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan ROC.
Jen-Shiou LinDepartment of Laboratory Medicine, Changhua Christian Hospital, Changhua, Taiwan ROC.
Chao Agnes HsiungInstitute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan ROC.
Jason C HuangDepartment of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan ROC.
Baoming JiangDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Jon R GentschDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Ministry of Health and Welfare · TWCenters for Disease Control and Prevention · USChang Gung Children's Hospital · TWChanghua Christian Hospital · TWChina Medical University Hospital · TWHUN-REN Veterinary Medical Research Institute · HUNational Health Research Institutes · TWNational Yang Ming Chiao Tung University · TW

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

The molecular characterization of genotype P[6] rotavirus strains collected from children admitted to hospital with acute dehydrating diarrhoea during a 6-year surveillance period in Taiwan is described in this study. In total, three G4P[6] strains, one G5P[6] and one G12P[6] were characterized by sequencing and phylogenetic analysis of the VP4, VP7, VP6 and NSP4 genes. Whilst all four genes of the single Taiwanese G12P[6] strain clustered with the respective genes of globally common human rotavirus strains, the G4 and G5 strains showed remarkable similarities to porcine rotavirus strains and putative porcine-origin human P[19] strains reported previously from Taiwan. The overall proportion of porcine rotavirus-like strains in Taiwan remains around 1 % among hospitalized children; however, the circulation and sporadic transmission of these heterotypic strains from pigs to humans could pose a public-health concern. Therefore, continuation of strain monitoring is needed in the vaccine era to detect any possible vaccine breakthrough events associated with the introduction of such heterologous rotavirus strains.

Indexed as

AnimalsChild, PreschoolCluster AnalysisDiarrheaGastroenteritisGenotypeHospitalsHumansRNA, ViralRotavirusRotavirus InfectionsSequence Analysis, DNASequence HomologySwineSwine DiseasesTaiwanRNA, ViralViral Proteins

Identifiers

PMID22466032
PMCPMC8167839
OpenAlexW2169558850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.