Evidence map›Paper›PMID 22462907›Full record

ArticleThe Review of scientific instruments2012

A wireless handheld probe with spectrally constrained evolution strategies for diffuse optical imaging of tissue.

M L Flexman, H K Kim, R Stoll, M A Khalil, C J Fong, A H Hielscher

Abstract read
In one paragraph

Article in The Review of scientific instruments, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Optical imaging for breast cancer prescreening.Breast cancer (Dove Medical Press) · 2015
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M L FlexmanDepartment of Biomedical Engineering, Columbia University, New York, New York 10027, USA. mlf2129@columbia.edu
H K Kim
R Stoll
M A Khalil
C J Fong
A H Hielscher

Funding

The Role of Inflammation and Stroma in Digestive CancerU54CA126513 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WANG, TIMOTHY CRAGIN · 2006 to 2010
$5.1M
Small Animal Tomography System for Green Fluorescent Protein ImagingR33CA118666 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HIELSCHER, ANDREAS H · 2008 to 2011
$1.1M
NCI NIH HHS 5R33CA118666NCI NIH HHS R33 CA118666NCI NIH HHS U54CA126513-039001
6 · The paper itself

Abstract

We present a low-cost, portable, wireless diffuse optical imaging device. The handheld device is fast, portable, and can be applied to a wide range of both static and dynamic imaging applications including breast cancer, functional brain imaging, and peripheral artery disease. The continuous-wave probe has four near-infrared wavelengths and uses digital detection techniques to perform measurements at 2.3 Hz. Using a multispectral evolution algorithm for chromophore reconstruction, we can measure absolute oxygenated and deoxygenated hemoglobin concentration as well as scattering in tissue. Performance of the device is demonstrated using a series of liquid phantoms comprised of Intralipid(®), ink, and dye.

Indexed as

Optical PhenomenaWireless TechnologyImage Processing, Computer-AssistedMolecular ImagingPhantoms, ImagingTime Factors

Identifiers

PMID22462907
PMCPMC3360692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.