ArticleISRN dermatology2012
A comparative analysis of mast cell quantification in five common dermatoses: lichen simplex chronicus, psoriasis, lichen planus, lupus, and insect bite/allergic contact dermatitis/nummular dermatitis.
Article in ISRN dermatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- The Potential Allergic Role of Mast Cells to Orthodontic Appliance in Orthodontic-Induced Gingival Enlargement.Oral health & preventive dentistry · 2026Article
- Mast cell - tumor cell interaction related gene and microRNA expression profiles in oral squamous cell carcinoma.Frontiers in oncology · 2025Article
- The Role of Mast Cells in the Induction and Maintenance of Inflammation in Selected Skin Diseases.International journal of molecular sciences · 2023Review
- Modulation of Immune Cells as a Therapy for Cutaneous Lupus Erythematosus.International journal of molecular sciences · 2022Review
- Psychological Stress, Mast Cells, and Psoriasis-Is There Any Relationship?International journal of molecular sciences · 2021Review
- Modern Imaging Technologies of Mast Cells for Biology and Medicine (Review).Sovremennye tekhnologii v meditsine · 2021Review
- Anti-fibrotic effects of the antihistamine ketotifen in a rabbit model of arthrofibrosis.Bone & joint research · 2020Article
- FACTORS CONTRIBUTING TO CHRONIC URTICARIA/ANGIOEDEMA AND NUMMULAR ECZEMA RESOLUTION - WHICH FINDINGS ARE CRUCIAL?Acta clinica Croatica · 2019Article
- Density of mast cells and intensity of pruritus in psoriasis vulgaris: a cross sectional study.Anais brasileiros de dermatologia · 2018Article
- Degranulated mast cells and TNF-α in oral lichen planus and oral lichenoid reactions diseases.Advanced biomedical research · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a large body of literature demonstrating an important role of mast cells in adaptive and innate immunity. The distribution of mast cells in the skin varies in different parts of the body. It is well known that mast cells are important for effector functions of classic IgE-associated allergic disorders as well as in host defense against infective agents and influence the manifestation of autoimmune diseases. We aimed to quantify mast cells in five common dermatoses and compare them statistically with respect to the immunostains. We retrieved paraffin-embedded tissue sections from the archives of the Pathology Department at the UF, Jacksonville, for five cases with each of the above diagnosis from the last three years. We performed CD-117 and tolidine blue stains on each one of them. The presence or absence of mast cells was evaluated and quantified. We observed that, in the skin, mast cells are mainly located close to the vessels, smooth muscle cells, hair follicles, and nerve ending. Our study showed that the mast cell distribution pattern is different across the two methods of staining for the five aforesaid dermatoses. The other important observation was the dendritic morphology of the mast cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.