Evidence map›Paper›PMID 22461988›Full record

ArticleISRN dentistry2012

In Vitro Antimicrobial Effect of a Cold Plasma Jet against Enterococcus faecalis Biofilms.

Chunqi Jiang, Christoph Schaudinn, David E Jaramillo, Paul Webster, J William Costerton

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ISRN dentistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chunqi JiangDepartment of Electrical Engineering-Electrophysics, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA.
Christoph Schaudinn
David E Jaramillo
Paul Webster
J William Costerton

Funding

Nanosecond pulsed plasma technology for endodontic biofilm disinfectionR21DE020167 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JIANG, CHUNQI, WEBSTER, PAUL · 2010 to 2011
$399k
NIDCR NIH HHS R21 DE020167
6 · The paper itself

Abstract

The hypothesis that a cold plasma jet has the antimicrobial effect against Enterococcus faecalis biofilms was tested in vitro. 27 hydroxyapatite discs were incubated with E. faecalis for six days to form a monoculture biofilm on the disc surface. The prepared substrata were divided into three groups: the negative control, the positive control (5.25% NaOCl solution), and the plasma treatment group. Resultant colony-forming unit counts were associated with observations of bacterial cell morphology changes using scanning electron microscopy (SEM). Treatment of E. faecalis biofilm with the plasma and 5.25% NaOCl for 5 min resulted in 93.1% and 90.0% kill (P < 0.0001), respectively. SEM detected that nearly no intact bacteria were discernible for the plasma-exposed HA disc surfaces. The demonstrated bactericidal effect of the plasma with direct surface contact may be due to the enhanced oxidation by the locally produced reactive plasma species.

Identifiers

PMID22461988
PMCPMC3302053

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.